What are the responsibilities and job description for the Scientist II / Senior Scientist, Immunology position at Vividion Therapeutics, Inc.?
Description
*Note: exact level depending on experience*
Company Overview
Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.
We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.
Vividion has been recognized as a Top Workplace by The San Diego Union-Tribune in 2022, 2023, and 2024.
Job Summary
We are seeking a motivated scientist to join our Immunology team, supporting our expanding portfolio of small molecules targeting autoimmune diseases. The Scientist will have a strong background in immunology with extensive hands-on experience in human immunology and in vitro experimentation using cellular, molecular, and immunological techniques. This position will be responsible for exploratory research to deepen understanding of mechanisms of action of our lead immunology assets, and for leading/supporting efforts towards validation of novel immunology drug targets. Responsibilities include establishing cellular and functional assays with human and mouse cells to study the impact of our compounds on innate and adaptive immune responses. Working closely with discovery, pharmacology, and translational teams, the candidate will contribute to execute on program strategies. Title will align with experience.
Requirements
Essential Duties and Responsibilities:
The anticipated base salary for this position ranges from $130,000 to $145,000 depending on relevant skills, competencies, experience, and education. In addition, this position is eligible for target bonus, long-term-incentives, 401k retirement savings plan with company match, and a comprehensive benefits package which includes medical, dental, vision, life, and disability insurance.
EEO & Employment Eligibility
Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Privacy Policy
The protection of your personal information is a commitment we take seriously. For information regarding our Privacy Policy (CA candidates) please visit https://vividion.com/publication/privacy-noticeforcalifornia-candidates/.
*Note: exact level depending on experience*
Company Overview
Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.
We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.
Vividion has been recognized as a Top Workplace by The San Diego Union-Tribune in 2022, 2023, and 2024.
Job Summary
We are seeking a motivated scientist to join our Immunology team, supporting our expanding portfolio of small molecules targeting autoimmune diseases. The Scientist will have a strong background in immunology with extensive hands-on experience in human immunology and in vitro experimentation using cellular, molecular, and immunological techniques. This position will be responsible for exploratory research to deepen understanding of mechanisms of action of our lead immunology assets, and for leading/supporting efforts towards validation of novel immunology drug targets. Responsibilities include establishing cellular and functional assays with human and mouse cells to study the impact of our compounds on innate and adaptive immune responses. Working closely with discovery, pharmacology, and translational teams, the candidate will contribute to execute on program strategies. Title will align with experience.
Requirements
Essential Duties and Responsibilities:
- Design and execute in vitro mechanism of action studies to support the therapeutic hypothesis for one of Vividion’s lead immunology programs
- Independently perform experiments, analyze data, interpret and communicate results to project teams.
- Stay abreast with the latest literature and recommend immunological study designs that will increase the confidence in therapeutic hypothesis
- Develop and/or use cutting-edge technology to support discovery research programs.
- Ph.D. in immunology with 3 years of relevant industry experience
- Expert knowledge of adaptive and innate immunity, including the roles of various immune cells and cytokines in immune regulation and understanding of biological principles underpinning immunological diseases.
- Proficiency in hands-on experience with flow cytometry assays, data acquisition, and analysis. Experience with multicolor panel design is highly desirable.
- High competency in executing in vitro immunology assays, including cellular-based assays and functional assays with cell lines, PBMCs, whole blood, animal samples.
- High competency performing techniques such as ELISA, Western blot, qPCR.
- Outstanding problem-solving, organization, and communication skills
- Effective troubleshooting and problem-solving skills.
- Excellent oral and written communication skills.
- Be an effective team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high-quality results under tight timelines.
The anticipated base salary for this position ranges from $130,000 to $145,000 depending on relevant skills, competencies, experience, and education. In addition, this position is eligible for target bonus, long-term-incentives, 401k retirement savings plan with company match, and a comprehensive benefits package which includes medical, dental, vision, life, and disability insurance.
EEO & Employment Eligibility
Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Privacy Policy
The protection of your personal information is a commitment we take seriously. For information regarding our Privacy Policy (CA candidates) please visit https://vividion.com/publication/privacy-noticeforcalifornia-candidates/.
Salary : $130,000 - $145,000
