Scheduled Hours

40

Position Summary

We currently seek a talented and self-motivated scientist who is looking to grow and contribute to a highly collaborative laboratory environment. The ideal applicant will have a solid foundation in several applicable skill sets and should be eager to grow and learn new techniques.

The lab of Dr. Albert (Gus) Davis studies the molecular and cell biology of protein aggregation and neurodegeneration, especially in the context of Parkinson disease (PD) and dementia with Lewy bodies (DLB). Using a combination of protein biochemistry, neuron and glia cell culture, and mouse models, the lab seeks to understand the molecular pathophysiology of alpha-synuclein aggregation (the main component of Lewy bodies), the gene and protein networks that regulate spreading of alpha-synuclein pathology within brain networks and the neurotoxicity and neuroinflammation that accompany this process.

Current projects in the lab include: 1) the role of apolipoprotein E (APOE) genotype, the strongest genetic risk factor for DLB, 2) the role of lysosomal enzyme variants associated with genetic risk of PD, 3) microglial clearance of pathogenic alpha-synuclein aggregates, and 4) the role of the adaptive immune system in PD pathogenesis.

Core techniques include molecular cloning, recombinant protein purification, biochemical protein assays including co-immunoprecipitation, ELISA, fluorescence seed amplification, primary neuron and primary glia cell culture, flow cytometry, immunocytochemistry (including confocal and live-cell microscopy), mouse husbandry and behavioral assays, stereotaxic surgery, perfusion and tissue dissection, histology, immunohistochemistry, stereology and other image analysis, and analysis of transcriptomic and proteomic data sets.

The Davis lab seeks to provide a supportive environment to foster scientific growth and personal development. We are committed to the highest standards of scientific integrity and are motivated to solve challenging biomedical questions to pave the way for development of improved tests and treatments for neurodegenerative diseases. Dr. Davis maintains a clear presence in the lab, meets regularly with individuals and team groups, prioritizes opportunities for lab member professional development, and strives to foster a dynamic and positive lab culture.

Job Description

Primary Duties & Responsibilities:

Working Conditions:

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range:

Base pay is commensurate with experience.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Bachelor’s degree or combination of education and/or experience may substitute for minimum education.

Certifications:

No specific certification is required for this position.

Work Experience:

No specific work experience is required for this position.

Skills:

Not Applicable

Driver's License:

A driver's license is not required for this position.

More About This Job

Candidates with additional education and experience are encouraged to apply.

Preferred Qualifications

Education:

No additional education beyond what is stated in the Required Qualifications section.

Certifications:

No additional certification beyond what is stated in the Required Qualifications section.

Work Experience:

No additional work experience beyond what is stated in the Required Qualifications section.

Skills:

Communication, Laboratory Research, Organizing, Recordkeeping, Working Independently

Grade

00

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity Statement

Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.