What are the responsibilities and job description for the Technical Assistant I - Oni Lab (Relocation Assistance Available!) position at Whitehead Institute?
Classification:
Exempt
Job Family:
Technicians
Reports to:
Whitehead Fellow
Job Description Summary:
The Oni Lab is dedicated to uncovering the molecular mechanisms that drive cellular interactions within the tumor microenvironment (TME), with a focus on identifying key effectors and developing innovative strategies to reshape these interactions for improved pancreatic cancer treatment.Our research leverages multimodal approaches to interrogate the tumor cell surfaceome and secretome, thereby uncovering critical mediators of tumor-stroma-immune interactions. These efforts are further supported by the development of cutting edge in vitro and in vivo pancreatic cancer models, which enable us to dissect the dynamic crosstalk among tumor, stromal, and immune cells. In parallel, we develop novel biologics to precisely target and disrupt tumor-promoting interactions, thus driving the development of potentially transformative therapies for pancreatic cancer.
The Oni Lab seeks a motivated research technician to support our studies on multicellular interactions in the tumor microenvironment and therapeutic development for pancreatic cancer. The role involves molecular biology, cell culture using tumor cell lines, organoids, fibroblasts, and primary immune cells. Additionally, the research technician will help with in vivo mouse models in a collaborative, dynamic, and intellectually stimulating research environment.
OVERALL RESPONSIBILITY
Performs bench level experiments and small independent research projects to support scientific research objectives of the lab. Performs in vitro and in vivo experiments, analyzes experimental data, addresses methodological problems in experimental protocols and results, and reports data to supervisor. Conducts laboratory tasks and organization to ensure the smooth operation of the group.
CHARACTERISTIC DUTIES
- In consultation with the Principal Investigator, designs and conducts bench level experiments in cell biology, biochemistry, and immunology.
- Performs experiments with mouse cancer models including handling, treating, and analyzing mice.
- Operates lab equipment and prepares and orders necessary supply stocks.May work with vendors to address equipment, reagent, or supply issues.
- Documents, compiles, and assists in interpreting experimental data.Reports data to the Principal Investigator in oral and written reports.
- Operate and maintain laboratory equipment to complete investigations.
- Prepares, orders, and maintains stocks of necessary reagents, solutions and supplies.
- Consults scientific literature as needed.
- Other tasks as required or assigned.
QUALIFICATIONS
- Bachelor’s degree in biology or a field directly related to the work.
- At least one year of experience and/or coursework in a biomedical research laboratory.
- Proficient in basic lab techniques and principles of molecular biology.
- Experience with cell or tissue culture.
- Knowledge of various scientific databases and publications.
- Excellent written and oral communication skills, strong organizational skills required.
- Experience with mice or other rodent models preferred.
Candidates with interest in pursuing advanced degrees in biology or medicine are encouraged to apply.
Whitehead Institute is an E-Verify employer
https://e-verify.uscis.gov/web/media/resourcesContents/E-Verify_Participation_Poster_ES.pdf
