Senior Scientist, Immunology

Our client, IntegerBio, is an early-stage biotech company based in Gaithersburg, Maryland, the center of the BioHealth Capital Region, just outside Washington, D.C., We are driven by a commitment to scientific excellence and our core values to Create Possibilities, Operate with Care & Candor, and Execute Purposefully. Led by industry veterans, we are a highly collaborative team focused on advancing our lead asset into the clinic, with a shared passion for transforming scientific innovation into meaningful outcomes. If you're inspired by bold science, purposeful execution, and working in an environment where teamwork and transparency thrive, we'd love to hear from you. Come join us and do the best work of your life. #pioneeringimmunovirology

The Opportunity: This is a role where the successful candidate can execute lab-based research while also providing coaching and guidance to other lab-based scientists. This requires strong time management, the ability to prioritize effectively and the capacity to shift gears seamlessly.

Direct scientific responsibilities include the design and execution of scientific research associated with IntegerBio's current and future assets to support successful development of new medicines. The incumbent collaborates with cross functional colleagues to discover and optimize novel therapeutics. Understanding disease pathogenesis in the context of viral infection and inflammation is key to this role.

Essential functions

Lab Based Research and Scientific Excellence (approximately 70% time)

• Design and execute research experiments by employing cutting edge innate/viral immunology, cell signaling and molecular biology techniques for in vitro/ex vivo and in vivo studies
• Participate in the design, execution and analysis of Preclinical and Clinical translation studies necessary to enable a planned IND for Integer's lead candidate.
• Analyze and interpret complex data sets, providing insights and recommendations for project advancement
• Collaborate with cross-functional teams to integrate immunological insights into broader research and development efforts as well as project strategy
• Stay abreast of the latest advancements in innate/viral immunology and contribute to the identification of emerging trends and technologies
• Contribute to the preparation and review of scientific publications, regulatory documents, and grant proposals.
• Present work at scientific meetings and publish findings

Scientific Leadership and Management (approximately 30% time)

• Translate strategic direction and oversee project execution and timeline management
• Collaborate with senior leadership to define scientific priorities and research goals, leveraging expertise in immunology to guide the design of experiments and contribute to the development of novel therapeutic approaches
• Ensure the successful planning, execution, and delivery of preclinical and translational research projects, balancing scientific rigor with timelines, budget, and resource allocation.
• Provide scientific guidance, direction and coaching to in-house research team and external research partners
• Manage external partners: Oversee engagements, including translational/clinical immunology studies delivered via CROs ensuring high-quality performance, timely deliverables, and alignment with the company's scientific objectives and regulatory standards.

Competencies

Technical Competencies

• Background in innate immunity and anti-viral immunity required
• Expertise in innate/antiviral Immunology and immune-mediated pathogenesis required
• Proficient in multiparameter Flow cytometry and analysis required
• Hands-on molecular biology (qRT-PCR, RNA-seq, Immunoblot), experience required
• Expertise in mammalian and human cell culture required
• Some experience in murine in vivo models required
• Experience in clinical immunology or translational sciences a strong plus
• Experience in developing high throughput cell-based functional assays a plus
• Ability to design and implement multiplex ELISA/ELIspot a plus

Professional and Management Competencies

• Experience executing R&D and translational science projects
• Ability to work cross functionally in a team-oriented environment
• Capacity to work independently
• Experience managing projects
• Experience mentoring, training and managing others required
• Ability to manage vendors
• Excellent written and communication skills required

Work environment This is a laboratory-based position, with time spent in the laboratory and office

Physical demands: Standing/sitting at the bench/desk for the majority of the day with breaks as needed, heavy lifting is not expected/required

Required education and experience: PhD in Immunology, Microbiology, Cell Biology or related field, with 2-5 years or more relevant experience (including in industry).

FLSA Classification Exempt

Salary Range Senior Scientist: $100,800 - $166,462

Reports to Head of Immunology

Individual base pay depends on various factors, including for example, an applicant's education, experience, skills, and abilities, as well as internal equity and market data. The salary may also be adjusted based on applicant's geographic location. This role is eligible for additional incentive compensation, including merit increases, annual bonus (depending on individual and company performance) and a new hire equity grant. Benefits include paid vacation and holidays; paid sick leave; health benefits including medical, prescription drug, dental, and vision coverage. Employees are eligible for these benefits on their first day of employment

EEO Statement: IntegerBio is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws

Contact: lauren.shue@integer.bio or katy.strei@integer.bio