What are the responsibilities and job description for the Staff Scientist - Research Associate 1 position at Yale School of Medicine?
Biological Electron Microscopy at Yale
Yale has a long history of excellence in biological electron microscopy (EM), It started with Dr. George Palade, a Nobel Prize-winning scientist and founder of modern cell biology. He pioneered the use of electron microscopy and other techniques to discover tiny structures within cells and to discern their functions, his work established our basic understanding of cellular organization. Over several decades, the EM facility has been continuously providing EM techniques to investigators for their biological research. We actively work with internal and external scientists providing EM services that include project consultation and experimental design, sample preparation, imaging with transmission and scanning electron microscopes. More recently, we have implemented cutting-edge techniques to support users who have needs to study 3D subcellular architecture, such as electron tomography (ET), focused-ion-beam scanning electron microscopy (FIB-SEM), or correlative imaging of fluorescence microscopy and EM (CLEM). In addition, we offer user training to Yale researchers who would like to independently operate electron microscopes or use other sample preparation equipment in the facility.
Role Description
Research Associate 1
CCMI - Center for Cellular and Molecular Imaging
Time Type
Full time
Duration Type
Regular
Work Location
Medical School Campus
Worksite Address
333 Cedar Street
New Haven, CT 06510
Work Week
Standard (M-F equal number of hours per day)
Searchable Job Family
Research Res Support, Research/Support
Total # of hours to be worked:
37.5
Position Focus:
Center for Cellular and Molecular Imaging (CCMI) Electron Microscopy (EM) Core Facility at the Yale School of Medicine offers cutting-edge instrumentation and expertise to the entire Yale scientific community. The selected candidate will join a diverse and highly skilled team engaged in a wide range of electron microscopy applications in the biological sciences. Daily responsibilities include working with investigators on various EM/Cryo-EM projects, assisting with experimental design, sample preparation, image data collection, and image processing and analysis.
The ideal candidate should be self-motivated, capable of delivering high-quality results promptly, eager to learn advanced EM techniques, and able to work both independently and as part of a team. This full-time, budgeted position offers ample opportunities for professional growth and development. The incumbent will report directly to the Core Facility Director.
Job Responsibilities:
- Prepare biological samples for transmission and scanning electron microscopy, including chemical fixation, resin embedding, ultramicrotome sectioning, and image acquisition.
- Train students and postdoctoral researchers on the use of electron microscopes and associated equipment.
- Learn advanced EM techniques, such as electron tomography, Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) for 3D volume imaging, high-pressure freezing, and immuno-EM procedures.
- Perform additional tasks as needed.
Required Education and Experience
Master’s Degree in a scientific discipline and one year of experience or an undergraduate degree with 3 years of experience, or equivalent combination of education and experience.
Required Skill/Ability 1:
Experience in sample preparation for microscopy and familiarity with the research lab setting.
Required Skill/Ability 2:
Familiar with cell biology and biological imaging techniques.
Required Skill/Ability 3:
Ability to produce high-quality work and deliver results in a timely fashion
Required Skill/Ability 4:
Reliability to work independently and support other team members
Preferred Education, Experience, Skills:
Strong knowledge of molecular and cellular biology, and experience with biological electron microscopy. Demonstrated ability to multi-task and excel in a fast-paced environment.
