What are the responsibilities and job description for the Graduate Research Fellowship in Biomarker Profiling and Computational Biology position at Zintellect?
The Department of Defense (DoD) is offering Graduate Fellowship at the U.S. Army Medical Research and Development Command - Medical Research Institute of Infectious Diseases (USAMRDC MRIID). Current graduate students or recent master's or doctoral degree recipients with interest and experience in computational biology and systems-based technologies are eligible to apply.
What will I be doing?
As an Oak Ridge Institute for Science and Education (ORISE) participant, you will join a community of scientists and researchers to understand host-pathogen interactions using systems-based technologies. We utilize an array of high throughput technologies exploring genomics, proteomics, metabolomics, transcriptomics, high content imaging and support the Institute with subject matter expertise and high-performance computing resources for computational biology. The participant will gain experience in a coordinated program of in vitro studies, small animal model work, and evaluation of control groups in ongoing NHP studies to provide a comprehensive profile of biomarkers (DNA Sequencing/Pathogen Characterization, RNAseq/transcriptomics, Mass spectrometry/proteomics and Raman Spectroscopy/metabolomics) to detect different pathogen disease states, further supporting field triage and intervention strategies. The Graduate Fellow may expect to be involved in the following project aims:
- Participating in the determination of diagnostic and triage potentials of Raman Spectroscopy for infection pathogens.
- Participating in the determination of diagnostic and triage potentials of Raman Spectroscopy for toxins.
- Participating in confirmatory mass spectrometry analysis.
Why should I apply?
Under the guidance of a mentor, you will gain hands-on experience to complement your education and support your academic and professional goals. You will also engage in activities and research in several areas. Unique learning opportunities of this Graduate Fellowship may include, but are not limited to:
- New proteomic methodologies and state of the art mass spectrometers, such as the timsTOF Ultra 2, to measure and identify peptides and metabolites in complex biological samples.
- Use of Resonance Raman spectroscopy (RSS) to provide differential identification of metabolites of high consequence pathogen or toxin insult.
- Investigate if RRS is sufficiently mature to describe biomarkers identifying toxins and high consequence pathogens at the family taxonomic level.
Where will I be located?
Frederick, Maryland
What is the anticipated start date?
August 15, 2025. Exact start dates will be determined at the time of selection and in coordination with the selected candidate. Applications are reviewed on an ongoing basis and internships or fellowships will be filled as qualified candidates are identified.
What is the appointment length?
This appointment is a twelve-month research appointment, with the possibility to be renewed for additional research periods. Appointments may be extended depending on funding availability, project assignment, program rules, and availability of the participant.
What are the appointment provisions?
You will receive a stipend to be determined by USAMRIID. Stipends are typically based on a participant’s academic standing, discipline, experience, and research facility location. Other provisions may include the following:
- Health Insurance Supplement (Participants are eligible to purchase health insurance through ORISE)
- Relocation Allowance
- Training and Travel Allowance
Security Clearance
While participants will not enter into an employment relationship with DoD or any other agency, this opportunity will require a suitability investigation/background investigation. Any offer made is considered tentative pending favorable outcome of the investigation.
About USAMRIID
USAMRIID's reputation has been built over the years by numerous scientists and technical staff working to protect both military personnel and civilians from the threat of infectious diseases. The Institute participates in support of emerging disease investigations, working alongside colleagues from the Centers for Disease Control and Prevention and the World Health Organization. As a reference laboratory for the Department of Defense, USAMRIID sets the standard for identification of biological agents. The Institute's workforce represents some of the top infectious disease and biological defense experts in the Nation—indeed, in the world. For more information about the USAMRIID, please visit https://usamriid.health.mil/.
About ORISE
This program, administered by Oak Ridge Associated Universities (ORAU) through its contract with the U.S. Department of Energy (DOE) to manage the Oak Ridge Institute for Science and Education (ORISE), was established through an interagency agreement between DOE and DoD. Participants do not enter into an employee/employer relationship with ORISE, ORAU, DoD or any other office or agency. Instead, you will be affiliated with ORISE for the administration of the appointment through the ORISE appointment letter and Terms of Appointment. Proof of health insurance is required for participation in this program. Health insurance can be obtained through ORISE. For more information, visit the ORISE Research Participation Program at the U.S. Department of Defense.
