Associate Scientist, In Vivo

Cambridge, MA

About Us

Aera Therapeutics was founded with a vision to unlock the potential of genetic medicines across a broad range of modalities and therapeutic areas.

Our novel protein nanoparticle (PNP) delivery platform is based on endogenous human proteins, leveraging the discovery of human proteins derived from retroelements that self-assemble to form capsid-like structures and which can package and transfer nucleic acid cargo. This platform combines the benefits of an endogenous, fully synthetic self-assembling system with the engineerability of a protein-based system and has the potential to enable various genetic medicine modalities.

With a world-renowned scientific founder and a distinguished Board of Directors, Aera has raised $193 million led by Arch Venture Partners, GV, and Lux Capital.

How will your role make an impact at Aera Therapeutics?

You will support our drug discovery platform from early drug discovery through translational research. You will support Aera’s exploratory research within multiple projects aiming for the development of a new generation of genetic medicines. You will collaborate with teams including Delivery Technologies, Formulation, PK/PD, Analytics, and Gene Editing providing critical support for Aera's success. You will report to the Associate Director, In Vivo Core Lead and will be required to come on-site five days per week.

You Will Be Responsible For

• Lead, execute and coordinate in vivo rodent studies across multiple projects. This includes managing animal well-being, conducting precise body weight measurements, administering compounds via multiple routes (IV, SC, IP), collecting blood samples, conducting clinical observations, and harvesting tissue samples.
• Implement rigorous organization, processing, and preservation protocols to prepare samples for subsequent analysis.
• Support ex vivo assays and analyses.
• Work with multiple teams to coordinate studies and data delivery, and help manage the mouse colony
• Maintain accurate and comprehensive records of study data within the laboratory information management system, ensuring data integrity and accessibility.
• Summarize, interpret and presenting data in internal meetings
• Perform study preparation and organizational activities.
  
  

Qualifications We Require For This Role

• Bachelor of Science (B.S.) degree in Biology, Pharmacology, Animal Science, or a related Life Sciences field, with 3 years of industry or academic experience, specifically in the field of in vivo biology
• Possess hands-on experience with rodent models, showcasing a practical understanding of their care and applicability.
• Uphold a high ethical standard, exhibiting a steadfast commitment to animal welfare principles.
• Exhibit expertise in routine dosing methods, including IV, SC and IP routes.
• Proficiently handle tissue collection and processes samples for subsequent analysis.
• Willingness to be cross-trained and execute ex vivo assays.
• Thrive in a collaborative environment, demonstrate strong teamwork skills, display desire and capacity to acquire new techniques and contribute to innovative projects
• Follow institutional and regulatory protocols, policies, and guidelines to maintain ethical and legal compliance.
• Commitment to our Core Values: Respect, Integrity, Impact, and Excellence
  
  

Benefits

• Healthcare
• 401K
• Flexible PTO
• Commuting subsidy
• Parental leave
  
  

Aera Therapeutics is committed to providing equal employment opportunities by recruiting, hiring, training and promoting applicants and employees without regard to race, color, religion, creed, national origin, sex, age, ancestry, sexual orientation, genetics, pregnancy, marital status, familial status, victim of domestic violence status, gender identity/expression, disability, handicap, military obligations, veteran status or any other category protected by federal, state or local laws.