What are the responsibilities and job description for the Research Associate, Formulation Development and Manufacturing position at Agios Pharmaceuticals?
Research Associate, Formulation Development and Manufacturing (FDM)
Who we are:
Agios is a biopharmaceutical company that is fueled by connections. We thrive in a supportive, fun, and flexible environment full of people empowered to bring their whole selves to work. We care deeply about our work, each other, and the patients who count on us. Our teams cultivate strong bonds with patient communities, healthcare professionals, partners and colleagues, which helps us discover, develop and deliver therapies for rare diseases – and make a bigger difference in their lives. In the U.S., Agios markets a first-in-class pyruvate kinase (PK) activator for the treatment of hemolytic anemia in adults with PK deficiency. Building on the company’s leadership in the field of cellular metabolism, Agios is advancing a robust clinical pipeline of investigational medicines with active and planned programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK deficiency and MDS-associated anemia.
The impact you will make:
Agios Pharmaceuticals is searching for a dynamic Research Associate / Senior Research Associate to join our growing Formulation Development and Manufacturing (FDM) team withing the Chemistry, Manufacturing and Controls (CMC) organization. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The Research Associate / Senior Research Associate will be responsible for supporting development of all FDM projects in collaboration with cross-functional teammates. The candidate will be responsible for driving a significant portion of Agios’ internal DP development including lab scale manufacturing and analysis. In addition, they will contribute heavily to the review and analysis of our external manufacturing processes and production (CDMO support). Finally, they will get experience with regulatory requirements by supporting review of internal source documents used in various regulatory submissions.
What you will do:
Location Specific – Onsite: This role requires the majority of work to be completed onsite at our Cambridge Headquarters. While it is expected that this role will be onsite a minimum of 4 days a week, Agios values flexibility, and flexible schedules around onsite work are available. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Employees in this role are expected to live within a commutable distance to the office.
What we will give you:
Who we are:
Agios is a biopharmaceutical company that is fueled by connections. We thrive in a supportive, fun, and flexible environment full of people empowered to bring their whole selves to work. We care deeply about our work, each other, and the patients who count on us. Our teams cultivate strong bonds with patient communities, healthcare professionals, partners and colleagues, which helps us discover, develop and deliver therapies for rare diseases – and make a bigger difference in their lives. In the U.S., Agios markets a first-in-class pyruvate kinase (PK) activator for the treatment of hemolytic anemia in adults with PK deficiency. Building on the company’s leadership in the field of cellular metabolism, Agios is advancing a robust clinical pipeline of investigational medicines with active and planned programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK deficiency and MDS-associated anemia.
The impact you will make:
Agios Pharmaceuticals is searching for a dynamic Research Associate / Senior Research Associate to join our growing Formulation Development and Manufacturing (FDM) team withing the Chemistry, Manufacturing and Controls (CMC) organization. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The Research Associate / Senior Research Associate will be responsible for supporting development of all FDM projects in collaboration with cross-functional teammates. The candidate will be responsible for driving a significant portion of Agios’ internal DP development including lab scale manufacturing and analysis. In addition, they will contribute heavily to the review and analysis of our external manufacturing processes and production (CDMO support). Finally, they will get experience with regulatory requirements by supporting review of internal source documents used in various regulatory submissions.
What you will do:
- Support solid oral dose formulation development in the Agios internal formulation laboratory
- Maintain a safe, functional and clean lab environment
- Assemble, disassemble, clean, operate and maintain different formulation equipment
- Support review, data collation and analysis of manufacturing batch records and reports
- Diligently records and presents experimental conditions, observations and results
- Solid state characterization such as XRPD, DSC, TGA
- Solid dosage form characterization techniques including HPLC, dissolution testing, flow and sticking assessments
- Author and review development reports
- Learn/ research various formulation process and analytical methods as needed to make progress with other duties
- Constantly develop and grow to support programs
- BS/MS in engineering, material science, chemistry, pharmaceutical sciences or related discipline with 0 – 3 years relevant experience.
- A knowledge of material science and basic chemistry is required
- Experience working in laboratories and author lab reports
- Excellent communication, presentation and writing skills
- A desire and aptitude to work with equipment is required
- Candidates with at least one prior internship, co-op or working in a college research lab are preferred but not required
Location Specific – Onsite: This role requires the majority of work to be completed onsite at our Cambridge Headquarters. While it is expected that this role will be onsite a minimum of 4 days a week, Agios values flexibility, and flexible schedules around onsite work are available. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Employees in this role are expected to live within a commutable distance to the office.
What we will give you:
- Deliberate Development. Your professional growth as one of our top priorities.
- We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best.
- Premium benefits package. We invest in the health, wellbeing and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team.
- Competitive performance-based compensation. This includes both short- and long-term incentives that are connected to our business strategy.
- Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.
- Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.
- Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.
