Demo

Senior Project Manager

Appleton Finn
Colorado, CO Full Time
POSTED ON 3/31/2025
AVAILABLE BEFORE 4/30/2025

Senior Project Manager – cGMP / Life Sciences

Location: Denver, Colorado

Industry: Life Sciences, cGMP, Pharmaceutical, Mission Critical

Position Type: Full-Time


About the Company

A highly respected general contractor with a strong presence in the Life Sciences, cGMP, and Mission Critical sectors is seeking a Senior Project Manager to lead and manage major construction projects. Known for its commitment to safety, sustainability, and innovation, this firm consistently delivers complex projects with a strong backlog and clear growth trajectory. Employees benefit from a collaborative culture, long-term stability, and clear pathways to career advancement.


About the Role

The Senior Project Manager will be responsible for leading cGMP, Life Sciences, and Mission Critical projects through planning, execution, and closeout. This role is ideal for individuals with expertise in pharmaceutical manufacturing (including peptide manufacturing), cleanroom environments, and high-tech facilities. The selected candidate will oversee project teams, coordinate with key stakeholders, and ensure that projects meet quality, budget, and schedule expectations.

This position also offers a clear pathway to a Project Executive role for individuals with extensive experience in cGMP, Healthcare, or Mission Critical projects, providing an excellent opportunity for long-term career growth.


Key Responsibilities

  • Provide strategic leadership on single or multiple cGMP / Life Sciences projects from preconstruction through completion.
  • Serve as the cGMP subject matter expert, particularly for large-scale or complex projects.
  • Work in collaboration with the Project Executive and leadership team to develop, manage, and execute project strategies.
  • Lead teams in Project Document & Data Management (PDDM), CQV/TOP documentation, and validation procedures specific to cGMP environments.
  • Develop and implement risk mitigation strategies, ensuring compliance with regulatory and quality standards.
  • Oversee subcontractor performance, ensuring adherence to project specifications and regulatory guidelines.
  • Drive budget, scheduling, and forecasting efforts to maintain profitability and project success.
  • Cultivate and maintain strong client and industry relationships, supporting business development efforts.
  • Ensure that all construction activities align with cGMP processes, procedures, and validation requirements.
  • Lead, mentor, and develop junior project managers, engineers, and field personnel, fostering a high-performing team.

Qualifications & Experience

  • 10 years of experience in construction project management, with a focus on cGMP, Life Sciences, or Mission Critical projects.
  • At least 5 years of experience with a general contractor or construction manager.
  • Experience managing at least one (1) peptide manufacturing facility project preferred.
  • Expertise in CQV/TOP procedures and validation processes required.
  • Strong leadership, organizational, and problem-solving skills.
  • Ability to manage multiple high-level projects while driving quality, schedule, and cost efficiency.
  • Bachelor’s degree in Construction Management, Engineering, Architecture, or a related field preferred.

Compensation & Benefits

  • Competitive Salary: $155,000 - $236,000 (DOE)
  • Annual Performance Bonus
  • Clear Upward Mobility to Project Executive for Senior-Level Candidates
  • Comprehensive Benefits Package (Medical, Dental, Vision, 401K Matching, PTO, etc.)
  • Company Vehicle or Allowance, Toll Pass, and Fuel Card
  • Employee Stock Ownership Plan (ESOP)
  • Strong Emphasis on Work-Life Balance & Career Growth

Why Join Us?

  • Strong project backlog and growth trajectory in Life Sciences and Mission Critical sectors.
  • Opportunity to advance into a Project Executive role for candidates with deep expertise in cGMP, Healthcare, or Mission Critical projects.
  • Work in a company culture that values collaboration, leadership, and innovation.
  • Be part of a firm that prioritizes employee retention, development, and career progression.


This is a confidential opportunity. If you are interested in advancing your career in cGMP, Life Sciences, or Mission Critical project management with a leading contractor, apply now to learn more.

Salary : $155,000 - $236,000

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