What are the responsibilities and job description for the Scientist I / II, Biologics Upstream Process Development position at Asimov?
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platformfrom cells to softwareto enable the design and manufacture of next-generation therapeutics.
We are seeking a Scientist I / II, Biologics Upstream Process Development to join our team in Boston, MA and help push the boundaries of biopharmaceutical and gene therapy process development. This role is for a technical expert who will conduct bioprocess engineering for biologics, design complex experimental approaches to improve our workflows and systems, apply scaling principles to upstream processing, and coordinate interdepartmental project efforts.
The successful candidate will work closely with Asimov's synthetic biology, cell line development, and analytical development teams, along with interfacing with external partners. The role reports to the Head of Process Development and is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
About the Role :
- You will be involved hands-on in projects that include media / feed optimization, bioreactor process development, process scale-up and characterization at Ambr15, Ambr250, and benchtop scale (2L / 10L).
- Serve as a technical subject matter expert (SME) in upstream process development for both internal and external projects.
- You will represent the process development team on cross-functional projects, making decisions for process development activities and effectively communicating results, progress, and plans.
- Work together with the strategic alliance and commercial teams to technology transfer developed upstream processes to external partners.
- Collaborate with internal process modeling team to test hypotheses for developing robust predictive models using DOE approaches, machine learning algorithms, and multi-omics analysis.
- Collaborate with the software team to develop integrated data platforms and analysis for streamlined data analysis.
- Author, review, and approve process development reports and technology transfer protocols.
- Organize and document experiments and data in an electronic lab notebook.
- Perform clarifications, downstream processing / purification, and product quality assessment with analytical tools when needed.
About You :
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
