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Pharmaceutical Sciences Intern

Beam Therapeutics
Cambridge, MA Intern
POSTED ON 2/26/2025
AVAILABLE BEFORE 5/23/2025

Company Overview :

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Position Overview :

Beam is looking for a highly dynamic and engaged individual to join the Technical Development Team from June through August 2025. The main goal of this internship will be to aid in the qualification of the mRNA platform production scale-down model. In this project, the Pharmaceutical Sciences Intern will be responsible for conducting high throughput mRNA manufacturing runs by utilizing Beam's automation infrastructure, performing and analyzing the quality of mRNA through analytical assays, assisting with ongoing process development projects, and utilizing Benchling capabilities by registering and updating equipment used in the lab.

Responsibilities :

  • Assist in qualification of Beam's mRNA platform production scale-down model.
  • Support automation development of high throughput mRNA manufacturing requests.
  • Assist in process development projects.
  • Learn and Analyze electropherograms to determine the quality of mRNA.
  • Carry out upstream plasmid isolation and purification tasks, as well as downstream mRNA purification tasks.
  • Help with integration of the Inventory functionality in Benchling software.

Qualifications :

  • Minimum AS degree, or currently in a BS program, in biology, chemistry, chemical engineering, biotechnology, or a related field.
  • Wet lab experience is required.
  • Some experience with liquid handlers, QC by using electrophoresis, plasmid isolation and purification, chromatography is preferred, but not required.
  • Candidate must be detail oriented, comfortable handling multiple projects, and is able to work alongside others well.
  • Must be able to work onsite.
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