Sr. Scientist / Principal Scientist – Neurodegeneration

About Us

Bexorg is a cutting-edge biotech startup focused on CNS drug discovery, leveraging its proprietary BrainEx platform to conduct preclinical studies on human and porcine brains. We combine advanced wet-lab experiments with AI/ML-driven drug discovery through our XO Digital platform to revolutionize the understanding and treatment of brain disorders. We are seeking a Senior Scientist/Principal Scientist with deep expertise in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, to contribute to our groundbreaking R&D efforts.

The Job

We are looking for a highly motivated and experienced Senior Scientist/Principal Scientist to lead key research and drug discovery programs. The ideal candidate will have extensive knowledge of Alzheimer’s, Parkinson’s or other neurodegenerative disease biology. This is a full-time, on-site position requiring physical presence in our state-of-the-art facilities to conduct hands-on research and collaborate directly with cross-functional teams.

Essential Duties/Tasks

• Lead scientific programs focused on identifying and validating new drug targets for neurodegenerative diseases.
• Oversee the design and execution of in vitro and in vivo studies to understand disease mechanisms, target biology, and drug response.
• Drive drug discovery programs using small molecules, biologics, or other therapeutic modalities from hit identification through lead optimization.
• Collaborate with cross-functional teams, including medicinal chemistry, pharmacology, and computational biology, to advance drug discovery projects.
• Apply cutting-edge techniques in neuroscience, including molecular biology, genetics, and advanced imaging to elucidate disease mechanisms and assess therapeutic approaches.
• Manage external collaborations with academic institutions, CROs, and industry partners.
• Mentor junior scientists and provide technical guidance and leadership across the research team.
• Stay abreast of the latest scientific advancements and contribute to the company’s overall strategy for neurodegenerative disease research.
• Present findings and progress to senior leadership, partners, and at scientific conferences.
  
  

Preferred Education And Experience

• PhD in Neuroscience, Biology, Biochemistry, Pharmacology, or a related field with 5 years of post-doctoral and/or industry experience.
• Deep expertise in neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, etc., with a strong track record of peer-reviewed publications.
• Hands-on experience with drug discovery, including target validation, lead optimization, and preclinical development.
• Proficiency in techniques such as cell-based assays, in vivo models, CRISPR, transcriptomics, proteomics, and imaging technologies.
• Proven ability to lead projects and mentor scientific teams.
• Strong problem-solving and critical thinking skills, with the ability to design innovative experiments and troubleshoot complex issues.
• Excellent written and verbal communication skills, with experience presenting data to internal and external audiences.
• Experience managing collaborations with external research partners and CROs is a plus.
  
  

Preferred Skills, Qualifications, Or Technical Proficiencies

• Experience with neuroinflammation, synaptic biology, or neuroimmune interactions.
• Familiarity with drug modalities including small molecules, antibodies, or gene therapies.
• Understanding of regulatory and preclinical development processes.
  
  

What We Offer

• Opportunity to work at the forefront of neuroscience and drug discovery.
• Collaborative work environment with a multidisciplinary team.
• Competitive compensation package including stock options.
• Career growth opportunities in a rapidly scaling company.
  
  

Bexorg, Inc. is an equal-opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.