Demo

Purification Process Development Scientist/Engineer

BioSpace
Indianapolis, IN Full Time
POSTED ON 1/19/2025
AVAILABLE BEFORE 2/17/2025
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$63,000 - $162,800

Synthetic Molecule Design and Development

Process Design and Development

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We are looking for people who are determined to make life better for people around the world.

Synthetic Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre-clinical phases through commercialization. Our scientists and engineers develop innovative technical solutions to advance an exciting portfolio that includes small molecules, synthetic peptides, oligonucleotides, and other emerging therapeutic modalities by cultivating a hardworking, culturally diverse workforce that exhibits deep technical expertise, SMDD delivers on these responsibilities to bring the next generation of life changing medicines to patients.

Our team is looking for motivated, creative, and energetic candidates to design and optimize purification processes to support Lilly’s synthetic molecule portfolio. This position will involve chromatography and filtration process development as well as analytical method development and characterization to deliver processes for small molecules, peptides, oligonucleotides, and conjugate molecules. In this role, the candidate will work in a dynamic team of purification scientists/engineers and analytical scientists to ensure successful delivery of our early and late-stage portfolio of synthetic molecules supporting pre-clinical, clinical, and commercial production. This work is critical for the development of robust purification processes that allow a consistent supply of Lilly medicines to patients. If you are excited about the opportunity to work with new modalities and provide innovative solutions to accelerate the development of cutting-edge medicines, this role is for you.

Top Candidates For This Position Will Be Expected To

  • Have a strong work ethic, scientific curiosity, and a hands-on problem-solving mentality
  • Demonstrate high learning agility with the ability to understand and exploit new scientific concepts and methods across multiple disciplines; be able to apply these learnings to a portfolio of small molecule, oligonucleotide, and synthetic peptide modalities.
  • Develop analytical and preparative-scale purification methods for isolation and characterization of API and target impurities with the ability to scale-up methods for material deliveries and GMP manufacturing
  • Explore new technologies and approaches for analytical and purification method development
  • Perform risk-assessments to help define the commercial control strategy for regulatory filing
  • Prioritize multiple projects on different molecules to meet project timelines
  • Collaborate closely with other functional areas including chemistry and analytical groups as well as external partners
  • Embrace diverse thought, background, and experience to deliver innovative solutions
  • Possess strong communication (oral, written), and organizational skills


Minimum Qualifications

  • B.S./M.S. Degree in Chemistry, Biochemistry, Chemical Engineering, or a related field


Additional Skills/Preferences

  • 2 years experience in analytical method development and/or purification development in the pharmaceutical industry (level commensurate with experience)
  • Experience with preparative chromatography
  • Experience with HPLC/UPLC and mass spectrometry
  • Good interpersonal skills and a sustained tendency for collaboration
  • Demonstrated initiative and risk-taking
  • Demonstrated technical proficiency and ability to create ideas for future work plans


Additional Information

  • Lilly is an EEO/Affirmative Action Employer, and does not discriminate on the basis of race, gender, protected veteran status, disability or any other legally protected status.
  • Travel: 0 to 10%
  • Position Local: Indianapolis, IN; Lilly Technology Center-North (LTC-N)


Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

Salary : $63,000 - $162,800

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