Senior Bioinformatics Scientist

At Boston Children’s Hospital, the quality of our care – and our inclusive hospital working environment – lies in the diversity of our people. With patients from local communities and 160 countries around the world, we’re committed to reflecting the spectrum of their cultures, while opening doors of opportunity for our team. Here, different talents pursue common goals. Voices are heard and ideas are shared. Join us, and discover how your unique contributions can change lives. Yours included.

Job Summary

Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge research ranging from lattice light-sheet microscopy to CryoEM, genomics, and informatics.

The role will work with PhD-level bioinformatics scientists and researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq and ChIP-seq data to investigate mouse and human diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. You will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. The ideal candidate should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies.

The Bioinformatics Scientist shall be responsible for:

• Providing computational support services to Boston Children's Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies.
• With minimal supervision and direction, completing highly complex assignments in the required timeframe; consistently adhering to and Promoting standard operating procedures and best practices; maintaining and upgrading a wide range of Research Computing tools, methods, and technologies, migrating data, documenting changes, and adjusting internal processes; resolving highly complex problems associated with assignments and seeking supervisor assistance when needed.
• Routinely leading, co-leading, or participating in complex Research Computing projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives; coordinating work activities with other stakeholders; contributing to the resulting presentations and/or publications.
• Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems.
• Creating or contributing to a range of compelling communications (e.g. PowerPoint presentations, e-mails, memos, scientific presentations, and publications) that clearly deliver even the most complex content and motivate action; preparing communications appropriate for management and internal distributions; reviewing and providing feedback on documents prepared by staff.

To qualify you must have:

• Minimum of 4-year Bachelor's degree in STEM. Minimum of five years of advanced bioinformatics experience. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related.
• Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc.
• Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. Cloud computing tools would be a bonus.
• Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research. Ability to routinely lead complex projects and coordinate project teams; readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians; ability to follow, improve and create technical documentation and standard operating procedures.
• Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audience; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums, and to develop training instructions and manuals.

Please apply on the Boston Children’s website - https://jobs.bostonchildrens.org/job/19919114/senior-bioinformatics-scientist/