Sr. Research Investigator , Clinical Pharmacology and Pharmacometrics

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more : careers.bms.com / working-with-us .The Clinical Pharmacology and Pharmacometrics (CP&P) team at BMS is responsible for the pharmacology and pharmacometric support for all pipeline assets throughout the clinical development lifecycle. Composed of pharmacologists, pharmacometricians, data scientists and modelers, this group oversees the pharmacokinetic evaluation, pharmacometric exposure-response evaluation, quantitative systems pharmacology modeling, physiologically based pharmacokinetic modeling and model based meta-analysis of assets covering all therapeutic modalities, including small molecules, traditional and complex biologics and next gen cell therapies. All therapeutic areas are supported.The CP&P team interacts with discovery and translational scientists, project leadership, early and late clinical development teams and commercial colleagues to provide input on clinical pharmacology profiling, dose optimization, formulation bridging, and combination strategies to enable faster and more effective drug development informed by core scientific principals and data.Responsibilities Independently contribute to compound development across various development phasesRepresent Clin Pharm on asset teams and at governance meetings based on proficiencyProvide input to Phase 2 / 3 clinical study design and registrational strategyAccountable for the Clinical Pharmacology PlanLead design of clinical pharmacology studies and manages data analysis, interpretation, and reportingHigh proficiency in PK, PK / PD, and model informed drug development (MIDD) principles and analysesCollaborate on cross-functional drug development teams, and regulatory submissions; serves as Clinical Pharmacology subject matter expertLead and participate in departmental initiatives and represent CP&P on cross-functional initiatives / workstreams / taskforcesParticipate in interactions with health authorities; serves as Clinical Pharmacology subject matter expertProvide critical expertise to Business Development teams to assess external acquisitionsRequirements Advanced Degree in related field (MS, Ph.D. or PharmD)For Associate Director level with Ph.D. approximately 5 years experience with demonstrated progression clinical pharmacology and Pharmacometrics experienceFor Sr. Research Investigator, with Ph.D. approximately 2 years experience with demonstrated progression clinical pharmacology and PharmacometricsFor Research Investigator, with Ph.D. approximately 0-2 years experience with demonstrated progression clinical pharmacology and PharmacometricsDemonstrated ability to work in a dynamic team-oriented environmentExpertise in general drug developmentExpertise in small molecule and / or biologic drug property characterizationDemonstrated stakeholder management with strong influence / leadershipQuantitative data analysis, POP PK / PD, and data visualization skillsProgramming experience (e.g., NONMEN, Phoenix NLME, Monolix, R, WinNonlin, SAS, Splus etc.)On-site ProtocolBMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role : Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations / adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation / adjustment prior to accepting a job offer. If you require reasonable accommodations / adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com / eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.#J-18808-Ljbffr