UNIV - Staff Scientist II - Department of Pharmacology

Job Description Summary Seeking highly motivated individuals for postdoctoral positions in neuroimmunology for projects that encompasses basic and translational research. Work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Ongoing projects involve investigating acute and chronic neuroimmune responses occurring after stroke or after different types of traumatic brain injury, including the long-term neurodegenerative sequalae of injury. For example, one project is focused on traumatic brain injury as a risk factor for Alzheimer’s Disease. Another project investigates pathogenic mechanisms of postnatal hemorrhagic stroke and neurodevelopmental consequences. Studies utilize various mouse models, and the laboratory is also developing several novel transgenic animals for these studies. Techniques currently utilized include advanced microscopy, cellular and molecular immune profile analysis, high dimensional analyses, and detailed assessments of motor and cognitive functions. The laboratory is also involved in the development (and commercialization) of novel therapeutic approaches, and has been a leader in the development of novel targeted complement inhibitory strategies. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001032 COM PHARM Administration CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Job Description Job summary Seeking highly motivated individuals for postdoctoral positions in neuroimmunology for projects that encompasses basic and translational research. Work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Ongoing projects involve investigating acute and chronic neuroimmune responses occurring after stroke or after different types of traumatic brain injury, including the long-term neurodegenerative sequalae of injury. For example, one project is focused on traumatic brain injury as a risk factor for Alzheimer’s Disease. Another project investigates pathogenic mechanisms of postnatal hemorrhagic stroke and neurodevelopmental consequences. Studies utilize various mouse models, and the laboratory is also developing several novel transgenic animals for these studies. Techniques currently utilized include advanced microscopy, cellular and molecular immune profile analysis, high dimensional analyses, and detailed assessments of motor and cognitive functions. The laboratory is also involved in the development (and commercialization) of novel therapeutic approaches, and has been a leader in the development of novel targeted complement inhibitory strategies. Duties/Responsibilities Participate in a project related to above described work, perform experimental procedures, including microsurgical procedures that include mouse models of stroke (ischemic and hemorrhagic) and traumatic brain injury. Prepare sections from mouse brains and process for histology and immune-microscopy. Perform various microscopy techniques. Evaluate mice via various behavioral tasks. 35% In terms of the above listed techniques, analyze and interpret data. Will also involve use of image analysis software and generation of computer images. Determine behavioral outcomes in terms of pathophysiological findings. 35% Collaborate with other lab personnel in related projects. Participate in lab meetings and project-specific meetings with other lab personnel. 15% Keep records and up to date lab notebook/lab archives. Assist with writing manuscripts and grants. Keep up to date with relevant literature. 15% Minimum Experience and Training Requirements: A PhD or equivalent in biology or other natural, life or health care science related to the assigned area of research. At least four years experience working in a research laboratory, and two years experience working in a related field to studies described above. For further information or to apply (CV and names of 3 referees), please contact Dr. Stephen Tomlinson: tomlinss@musc.ed MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience plus evidence of scholarly activity as demonstrated by at least five first author publications. MUSC Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Must be ambidextrous. Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees Thank you for wanting to be part of the Medical University of South Carolina team. Whether you want to teach the next generation of health care leaders, innovate new business models, discover the next breakthrough or provide patient care, there's a role for you that fuels your passion and takes advantage of your skills. There are career opportunities available in academics, research, hospital medicine, physician practices and support services, from patient billing to IT. As an applicant, you can search jobs for all MUSC entities as well as search by category and location. MUSC attracts more than $250 million annually in research funding, making it the biggest magnet for biomedical, extramural research dollars of all institutions of higher learning in South Carolina. The Clinical and Translational Science Award (CTSA) Program aims to advance clinical and translational science to increase the speed at which new treatments become available to patients. MUSC Health, the clinical enterprise, operates a 750 bed medical center, which includes a nationally recognized Children’s Hospital, the Ashley River Tower (cardiovascular, digestive disease, and surgical oncology), Hollings Cancer Center (one of fewer than 70 elite National Cancer Institute designated centers), a Level I Trauma Center and the Institute of Psychiatry. In addition, there are more than 100 outreach clinics, hospital/health system affiliations, and telehealth sites. U.S. News & World Report placed us among the top one percent of all American hospitals, with 11 specialties in the top 50. The MUSC Medical Center is also one of only three Magnet® designated hospitals in South Carolina.

Salary : $250