What are the responsibilities and job description for the Associate Scientist, Analytical Development, Bioassay position at Denali Therapeutics?
Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Key Accountabilities/Core Job Responsibilities:
Independently perform bioassays to support cell-line, bioprocess, and formulation development activities
Assist in the development, optimization, and qualification of assays for product release and stability testing as well as characterization of biological activity.
Support study sample testing, analysis and maintain complete and accurate records and contribute to continuing process improvement
Evaluate, characterize, and document critical reagents to meet QC standards
Coordinate parallel tasks across multiple projects and prioritize deliverables to meet departmental and organizational goals.
Promote innovation and explore novel analytical techniques or technology.
Qualifications/Skills:
BS with 3 years of industry experience or an MS 1 years relevant experience in the industry
Experience in developing and optimizing bioassays across multiple platforms and technologies (e.g., ELISA, HTRF, DELFIA, fluorescence, etc.) is required.
Strong expertise in nucleic acid techniques, including DNA manipulation, PCR, qPCR, DNA quantification, analysis, and hybrid capture.
Experience in developing or running assays with automated liquid handling systems isa plus.
Proficient in data analysis with Excel and statistical tools such as GraphPad Prism, SoftMax Pro, PLA, and JMP. Familiar with electronic notebooks and documentation workflows. Basic statistical programming is a plus.
Ability to balance competing priorities and thrive in a dynamic, fast-paced environment
Excellent laboratory, critical thinking, scientific problem-solving, and organizational skills
Excellent oral and written communication skills
Motivated, detail-oriented, naturally curious individual with a creative approach to scientific problem solving and a burning desire to help patients with neurodegenerative diseases.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
