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Senior Clinical Scientist

Denali Therapeutics
South San Francisco, CA Full Time
POSTED ON 1/22/2025
AVAILABLE BEFORE 4/12/2025

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

Key Accountabilities / Core Job Responsibilities :

  • Contributing to or leading the development of clinical protocols, informed consents and other study related materials
  • Drafting clinical sections of study reports, investigator brochures, responses to regulatory authorities and other key clinical and regulatory documents
  • Ensuring high quality clinical trial conduct and data collection (e.g. safety, biomarker, imaging and COA data) through on-study clinical data monitoring
  • Partnering with clinical operations and other teams for successful execution of clinical studies
  • Working closely with medical monitor on clinical activities, monitoring the safety of trials, and clinical site interactions
  • Reviewing and analyzing clinical data
  • Engaging in topical literature review on discrete topics to support development program success.
  • Representing clinical science on cross functional teams

Qualifications / Skills :

  • BS / MS degree (science based) is required with PharmD, PhD, MD preferred
  • 7 years of industry experience
  • Strong oral / written communication skills
  • Demonstrated experience in protocol authoring, study startup, study execution / monitoring and data review activities
  • Experience contributing to global regulatory filings such as INDs or CTAs; experience in NDA or BLA filings a plus
  • Experience in implementation of biomarkers and / or imaging in clinical trials is highly desirable
  • Skilled in scientific data analysis, interpretation, and results reporting
  • Therapeutic experience in neurology, rare diseases or pediatrics preferred
  • Ability to work independently and collaborate on cross-functional teams is required
  • Can do," "pitch in" positive attitude
  • Salary Range : $165,000.00 to $204,333.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https : / / www.denalitherapeutics.com / careers

    This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.

    Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and / or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

    Salary : $165,000 - $204,333

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