Demo

Principal Scientist, Computational Biology

Enveda
Boulder, CO Full Time
POSTED ON 3/3/2025
AVAILABLE BEFORE 3/29/2025
Proud to be recognized as one of Forbes' America's Best Startup Employers!

Enveda is looking for a Principal Scientist in Computational Biology to join our team in Boulder,CO. !

The Contribution You Will Make

We are looking for a Computational Biologist (Principal Scientist) with a strong background in proteomics and transcriptomics data analysis using Python and/or R and experience deconvolving complex biological signals in preclinical and clinical settings. As part of the Mechanism of Action (MOA) and Target Identification team, you will lead the analysis of large multi-omic data sets, supporting the advancement of our pioneering, nature-inspired medicines. Your work will directly contribute to developing first-in-class small molecule therapeutics at Enveda.

You Get To Collaborate On

  • Design and implement computational workflows and infrastructure to identify novel therapeutic mechanisms from drug perturbation omics experiments and human clinical trial data
  • Develop novel algorithms to integrate proteomics, transcriptomics, and metabolomics data with phenotypic data (in vitro, in vivo, ex vivo, preclinical models) to determine the mechanisms of action of our medicines
  • Discover novel biomarkers from human clinical data demonstrating target-engagement of clinical and preclinical candidates
  • Lead the experimental design, execution, and analysis of preclinical MOA experiments,
  • Develop infrastructure to rapidly analyze and visualize high-dimensional biological data

Who will thrive in this role?

  • Ph.D. in Computational Biology, Systems Biology, Bioinformatics, Chemical Engineering or a related field
  • Over 5 years of post-PhD industry experience
  • Proven success in collaborative projects related to elucidation of disease mechanisms in preclinical and clinical settings
  • Expertise in analyzing large-scale multi-omics data particularly proteomics and transcriptomics
  • Strong foundation in statistical modeling
  • Deep familiarity with modeling in Python and/or R
  • Ability to summarize complex results in concise written form and present to diverse audiences
  • If you don't meet all of the requirements listed here, we still encourage you to apply. No job description is perfect, and we might find an even more suitable opportunity that matches your experience.

What To Expect In The Interview Process

  • HR Screen (30 minutes)
  • Hiring Manager Interview (45 minutes)
  • Take Home Work Sample (4 hours)
  • Work Sample Interview (60 minutes)
  • Technical Interview (45 minutes)
  • Enveda Culture Interview (30 minutes)

Some of the total rewards of working here

  • Culture: Enveda lives for people
  • Salary: $175,000 - $200,000
  • Equity
  • Healthcare: Medical, dental and vision insurance. Company pays 90% of the premium for employee and dependents.
  • 401k: Traditional or Roth 401k matching of 4% (100% of your contributions up to 4% of your annual compensation).
  • PTO: Flexible paid time off (that we encourage and celebrate). Company-wide weeklong break to recharge. 10 observed holidays.
  • Work-Life Harmony
  • Adoption Assistance: At Enveda we want to celebrate and support employees who want to adopt children. We're excited to offer adoption assistance to employees who have completed the adoption process, including placement.

Come join us!

Our employees are the lifeblood of our work and our inspiration to press on. Together we've built a special place here—a drug discovery platform that's unique in the world with an incredible team collaborating in a creative, transformative culture. Our mission is to bring hope to patients everywhere. Our progress towards that goal would not be possible without talented people like you.

Employee Promise

Using our imagination and dedication, we are working to improve human health and give hope to patients everywhere. Our work together is empowering, trustable and collaborative, enabling you to do your best work.

Enveda's values

Curiosity: Learn and challenge.

Agency: Own and initiate.

Journey: Love the process.

Charity: Take care of each other.

Unity: We are one Enveda.

We value your uniqueness

One of life's gifts is to interact with a variety of people. Each of us has a unique story that shapes how we view the world, and solve problems. Learning from each other enhances our collective wisdom while achieving better outcomes at a faster clip. People from all kinds of backgrounds can succeed in all kinds of roles.

Our work environment appreciates the contributions of every person. Working together is how we produce results that illuminate our Purpose - To Deliver Hope To Every Patient. Unity is a company value because success depends on trusting, working relationships that respect the commonality and differences of people.

At Enveda we are building a place where every person can do the best work of their lifetime.

Enveda is an equal opportunity employer. We do not discriminate on the basis of characteristics protected by federal, state or local laws.

  • Please note jobs may be taken down from our website, this does not mean they have been filled. This is to maintain our candidate experience for current applicants. If you are in the interview process and would like to request a copy of the job description, reach out to your recruiting contact.

Salary : $175,000 - $200,000

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