What are the responsibilities and job description for the Scientist / Senior Scientist - Assay Development position at GC Therapeutics?
Scientist / Senior Scientist – Assay Development
Company Overview
GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency, and speed. GC Therapeutics is based in Cambridge, MA. For additional information, please visit
Job Purpose
GC Therapeutics is seeking a talented and highly motivated Scientist to support the qualification and validation of assays for the testing, characterization, and release of novel Pluripotent Stem Cell (PSC) derived products. This individual will be expected to design and execute experiments that determine assay performance including the assessment of assay specificity, accuracy, precision, linearity, range, reproducibility, robustness, and ruggedness.
Duties and Responsibilities
- Design, develop and validate assays for testing the safety and efficacy of stem cell-derived drug substances, products, and critical starting material.
- Analyze data and contribute to complex technical reports and team meetings.
- Contribute and author module 3 documents including analytical procedure development and validation of analytical procedures necessary for IND submissions.
- Develop procedures and protocols for the genetic, transcriptomic, proteomic, and functional characterization of pluripotent stem cells and their derivatives.
- Qualify and validate product specific assays to determine identity, purity, and potency of PSC derived products including various cell based assays, flow cytometry, immunohistochemistry, ELISA, and ddPCR.
- Prepare complex technical reports including SOPs, test methods and method development reports.
- Lead the transfer of assays to quality control (QC) team and external contract manufacturing organizations as needed.
- Contribute to team and company presentations.
General Laboratory Roles :
Experimental Techniques :
Cellular Biology :
Molecular Biology :
Qualifications
Essential Qualifications :
Additional Preferred Qualifications :
Equal Opportunity Workplace : GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics’ equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.
