Associate Scientist, Physico-Chemical Characterization (Separations)

Associate Scientist, Physico-Chemical Characterization (Separations)

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At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we've invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK's long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.

In the plan to create a new hub for mRNA-based vaccine discovery in Cambridge, we are building new laboratories that will be focused on the development of state-of-the-art methods that will be supporting deep product understanding, process and product development, as well as testing of pre-clinical and clinical samples for new mRNA-based vaccines.

As an Associate Scientist, you will perform analytical development alongside a team of scientists to support early-stage product understanding in a variety of vaccine platforms; with a focus on mRNA, mRNA-LNP, and protein characterization methodologies.

Key Responsibilities:

• Work alongside scientists to help develop HPLC/UPLC/CGE methods to characterize mRNA, DNA, proteins, N-glycans, lipids, and vaccine components.
• Perform routine biophysical characterization methods as necessary, which include HPLC/UPLC, CGE, LC-MS, LC-MS/MS, GC, light scattering, particle characterization, spectroscopy, calorimetry, or other compendial tests as needed
• Preparation of samples for characterization studies
• Maintain records thorough electronic lab notebooks and documentation records
• Deliver reproducible and impactful results under ambitious timelines
• Execute and troubleshoot standard protocols, develop and adapt new protocols into practice to improve assays as needed.

The successful applicant will spend approximately 25% of their time for 1-3 months within the first year in Rockville, MD to support and guarantee a smooth transition of methods and know-how to the new laboratories in

Cambridge, MA.

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• Bachelors/Masters in Sciences/Engineering discipline with experience in biological systems
• 1 years experience (for Bachelors) and 0 years experience (for Masters)
• One or more years of experience in developing separation analytics (HPLC/UPLC/CGE) of large biomolecules (mRNA, DNA, or Proteins)

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• One or more years of experience with Capillary Gel Electrophoresis
• mRNA-LNP vaccine analytics or vaccine development experiences
• Strong verbal and written communication skills; good presentation skills
• An adaptable team player with a passion to learn
• Meticulous and motivated lab scientist with demonstrated experience
• Strong theoretical and practical background in proteomics and biophysical characterization methodologies

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Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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