Staff Scientist, Applied Science in Therapeutic Oligonucleotides

Integrated DNA Technologies (IDT) is the leading manufacturer of custom oligonucleotides and proprietary technologies for genomics applications. Our work is complex and cutting-edge, and our team members are curious, creative thinkers who understand that good data drives smart decisions. At IDT, we realize that although science may be uniform, people are unique. We promote a culture where engaged people are motivated and have opportunities to achieve their full potential, as part of one global team.

Read the overview of this opportunity to understand what skills, including and relevant soft skills and software package proficiencies, are required.

IDT is one of 10 Life Sciences companies of Danaher. Together, we accelerate the discovery, development and delivery of solutions that safeguard and improve human health.

This position is part of the Applied Sciences for Therapeutic Oligonucleotides team in our Gene Writing and Editing Business Unit located in Coralville, Iowa and will be on-site . At IDT, we are one global team. We celebrate our differences, engage in healthy debate, and are inclusive. Together, we accomplish great things!

In this role, you will have the opportunity to :

• Function as the lead scientist driving and executing projects as part of IDT’s new Genomics Medicine Service offerings related to : off-target safety assessment for CRISPR-based editing systems, CRISPR guide RNA sequencing, and additional, custom projects associated with IDT’s Therapeutic Oligonucleotides business.

Provide leadership, training, planning, etc. related to all aspects of therapeutic oligonucleotides projects inclusive of lab work, project tracking and organization, data collection, data analysis, report generation, and data presentation

Demonstrate skills as a technical expert integral to facilitating technology transfer of methods from R&D to the Gen Meds Services team; additionally, provide plans to execute further feasibility, development and validation of assays for broader use and application

Lead projects and lend subject matter expertise to customer-specific oligo assessment of quality, performance, safety, etc. in cell-based, biochemical or analytical assays; help to define technical and experimental work plans related to these efforts to advance customer projects while supporting customer progress towards cGMP oligonucleotide synthesis.

The essential requirements of the job include :

Bachelor’s degree (in Biology, Genetics, Chemistry or a related life sciences field) with 10 years relevant lab experience OR a Master’s degree (in Biology, Genetics, Chemistry or a related life sciences field) with 8 years relevant lab experience OR a PhD degree (in Biology, Genetics, Chemistry or a related life sciences field) with 5 years relevant lab experience

Demonstrated experience and technical background in CRISPR and Gene Editing rooted in research, development, or applications.

Demonstrated expertise in CRISPR-based editing technologies via peer-reviewed publication record or product development history.

Demonstrated expertise in cell culture techniques, delivery of genome editing components to various cell types, and management of good laboratory practices in a tissue culture lab.

Demonstrated strong experience in next-generation sequencing technology development and / or application, including demonstrated ability of critical thinking applied to experimental planning, data analysis and data presentations

Travel, Motor Vehicle Record & Physical / Environment Requirements :

Ability to travel domestically and internationally approximately 10%

It would be a plus if you also possess previous experience in :

Delivering results in a regulated space (GLP, ICH, cGMP, etc.).

Bioinformatics related to assessment of genome editing or working with bioinformatics experts towards NGS-based assessment of genome editing events

Operating under design control and design assurance in product development

Custom genomics product development, verification or validation

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.

For more information, visit www.danaher.com.

Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.

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We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation.