Scientist (Protein Characterization)

Job Description:

The Characterization and Developability teamwork integrated with other teams within Protein Sciences Department as well as Therapeutic Area discovery project teams and plays a pivotal role in early biologics discovery by engaging in high throughput biophysical screening, molecule optimization and developability assessments to enable selection of the best candidate molecule for further development.

• The successful candidate is expected to have experience in protein chemistry and biophysical characterization of biologics using a variety of analytical tools – chromatographic, electrophoretic, light scattering and other analytical methods.
• The ideal candidate will have hands-on experience in characterization of monoclonal antibodies (mAbs), bi-/multi-specifics, fusion proteins, antibody drug conjugates (ADCs), etc.

Education Requirement: BS/BA degree in Biophysics/Biochemistry or related field with 4 years of relevant experience or MS degree in Biophysics/Biochemistry or related field with 2 years of relevant experience, PHD with 0-1year.

Experience and Skills:

• Hands-on expertise in analytical characterization of proteins using a wide range of physicochemical characterization methods such as SEC, SEC-MALS, HIC, CE-SDS, cIEF, DLS/SLS, DSF, etc. Strong understanding of protein structure, biophysics, and analytical mindset to enable understanding of the relation between physicochemical properties and proteins structure/sequences
• Previous experience with analytical characterization and developability assessment of biologics highly desired
• Experience/Interest with high-throughput analytical characterization workflows Strong analytical skills and attention to detail
• Ability to work on multiple projects and ability to meet aggressive timelines
• Documentation of procedures, methods, data, and results in electronic laboratory notebooks
• Team player and excellent interpersonal skills
• Strong communication and presentation skills