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Research Associate I, Manufacturing & Operations

Ionis
Carlsbad, CA Full Time
POSTED ON 4/6/2025
AVAILABLE BEFORE 5/2/2025

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We are pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With five currently marketed medicines for serious diseases and an expansive late-stage pipeline, we continue to build upon our groundbreaking innovations in science and technology to provide greater value to patients; and we are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know our success is a direct result of the exceptional talent and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money, and energy into making our onsite and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We are building on our rich history, and believe our greatest achievements are ahead of us. We invite you to apply and join us if you're passionate about the opportunity to have meaningful impact on patients in need, our employees, and our organization. Experience and contribute to our unique culture while you develop and expand your career!

Research Associate I

SUMMARY :

Ionis is seeking a highly motivated and talented individual to join our Drug Substance Manufacturing team as an entry-level Research Associate I working in a collaborative large-scale GMP manufacturing environment. Job duties will focus on synthesis and purification of oligonucleotides, preparation of GMP solutions, operation, cleaning and troubleshooting large-scale equipment, and revising Standard Operating Procedures (SOPs) to support manufacturing. Additionally, the individual will participate in safety trainings, act as a member of the Emergency Response Team (ERT) and be able to respond to any on-site emergencies.

RESPONSIBILITIES :

  • Work in a GMP cleanroom environment and comply with quality regulations
  • Operate large-scale, computer-automated equipment in the GMP synthesis and purification of oligonucleotides
  • Clean GMP equipment and tanks
  • Author, revise, and execute SOPs, automated methods, and batch records
  • Formulate intermediate and buffer solutions
  • Participate in safety trainings and as an Emergency Response Team (ERT) member
  • Initiate projects and manage multiple assignments and tasks, establishing inter-department communications to monitor expectations and timelines
  • Safety- focused and willing to work with hazardous chemicals and pressurized equipment
  • Exhibit the qualities of an energetic, positive, self-motivated, hands-on professional with strong work ethic
  • Maintain productivity and efficiency both independently and with a team in an intense, data-driven, interrogative environment

REQUIREMENTS :

  • B. S. degree in Chemical Engineering, Chemistry, or related field
  • GMP industry experience required. Prefer at least 1 year of experience.
  • Oligonucleotide manufacturing experience a plus
  • Comfortable wearing Personal Protective Equipment (PPE) and respirator
  • HAZWOPER certification a plus
  • Ability to work extended hours with frequent standing, pushing and lifting (up to 50 lbs.)
  • Proficient in MS Office applications with Unicorn, Veeva, LabWatch, and process control software a plus
  • Please visit our website, http : / / www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS003629

    Ionis offers an excellent benefits package! Follow this link for more details : Ionis Benefits

    Full Benefits Link : https : / / www.ionis.com / careers / working-at-ionis / # : ~ : text=our employee spotlight-,Benefits,-Employees are rewarded

    The pay scale for this position is $68,640.00 -$89,319.00

    NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

    Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

    Salary : $68,640 - $89,319

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