What are the responsibilities and job description for the Senior Scientist I, Protein Characterization Mass Spectrometry position at Johnson & Johnson Innovative Medicine Brasil?
DescriptionJohnson & Johnson is recruiting for a Senior Scientist, Protein Characterization by Mass Spectrometry located in Malvern, PA.At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.At Johnson & Johnson, we all belong.The Senior Scientist will work in the Characterization group within Analytical Development to independently develop, design and perform mass spectrometry assays in support of product characterization and process development activities. Duties and responsibilities include but are not limited to:
- Design and execute LC/MS assays for characterizing mAb and non-mAb products.
- Write protocols, reports, and coordinate testing across functional groups to support analytical development, manufacturing process development, process validations, manufacturing investigations, structure/function characterization, and IND/BLA filing.
- Participate in cross-functional teams at project-related meetings, lead/facilitate technical discussions
- Maintain laboratory notebooks and prepare written protocols and reports in a Good Manufacturing Practice (GMP) compliant manner.
- Bachelor’s degree is required
- Master’s degree or PhD is highly preferred
- Minimum of 10 years of experience following the completion of a Bachelor’s Degree OR minimum of 5 years of experience following the completion of a Master’s Degree OR minimum of 0-2 years of experience following the completion of a PhD in Analytical Chemistry, Biochemistry, Biotechnology, Protein Formulations, Chemical Engineering, or a related field
- Hands-on experience with Mass Spectrometry is required
- Ability to balance and contribute to multiple project priorities is required
- Ability to independently work across other functions (regulatory, QC, process development) to drive studies is required
- Good written and verbal communication skills are required
- Experience with characterization of antibody drug conjugates (ADCs) is preferred
- Experience working cIEF/MS, disulfide bond analysis, native MS, etc. is preferred
- Experience with 3rd party MS software (eg., Protein Matrix, Genedata Expressionist, etc.) is preferred
- Experience and understanding of pharmaceutical development chemistry, manufacturing and controls (CMC) processes and regulatory requirements for protein biologics is preferred
- Experience working in a GLP/GMP environment is preferred
