What are the responsibilities and job description for the Scientist, mRNA, Cell and Molecular Biology at Kudo Biotechnology position at Kudobio?
Scientist, mRNA, Cell and Molecular Biology at Kudo Biotechnology
2 / 22 / 2024
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Kudo Biotechnology Inc. (Kudo) is a global mRNA-focused contract development and manufacturing organization (CDMO). Kudo has a state-of-the-art clinical GMP manufacturing facility and Manufacturing Sciences & Analytical Technology (MSAT) laboratories in Shanghai, China, as well as a Process Science Center of Excellence in Needham, MA, where Kudo operates mRNA / LNP process and analytical development labs.
About the role
We are seeking a highly motivated, scientifically curious, and collaborative scientist to grow our process and analytical development team. The successful candidate will be an integral part of our team, whose aim is to research, develop and advance mRNA manufacturing technology and analytical sciences. This role is primarily a lab-based position, where you will work in a cross-functional team and interface with internal and external stakeholders to accelerate the development effort. This will be a great opportunity to be exposed to aspects of mRNA process and analytical development in a fast-paced, dynamic, and collaborative environment.
Responsibilities
- Lead, design, and optimize research with the aim of exploring and developing improved mRNA manufacturing processes and analytical methods using molecular and cellular biology techniques.
- Develop, document, and transfer bioassays (e.g. cell-based in vitro potency assay, reporter gene assay for dsRNA detection) in support of internal mRNA and lipid nanoparticle (LNP) process development efforts and external project execution.
- Plan and execute studies requiring molecular biology techniques including E. coli cell culture, plasmid preparation, RNA synthesis, and purification with the aim to develop the processes that can be scaled up and transferred to MSAT labs.
- Perform mRNA production and characterization by conducting bioanalytical assays following established protocols and SOPs and prepare study reports.
- Perform data analysis, troubleshooting experiments, and recording results in electronic lab notebook. Share data within the team with high quality and clarity.
- Collaborate across multiple cross functional teams. The ability to effectively communicate within a project team and with external partners is expected.
- Stay aware of the process technology advancements and new DNA / RNA modalities through publications, presentations, patents, and industry workshops.
Qualifications
Please email a cover letter and resume to kudo.hr@kudobio.com
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