Laboratory Technician

Job description

The MA LAB for immune engineering and translational immunology at the

University  of   Pennsylvania  and  Children’s  Hospital  of  Philadelphia

(https://www.malabimmuneng.com/)  is  seeking  a  motivated research

assistant to join our innovative laboratory to carry out cutting-edge research

on immune system crosstalk and engineer innovative biomaterials, protein

and  cell-based  immunotherapies.   We  are  a  highly  interdisciplinary  team

working at the interface of immunology and engineering. We leverage 1)

Chemical and biomaterials engineering to dissect and manipulate immune

cell-cell and cell-tissue crosstalk to enhance cellular therapy and promote

vaccine development, 2) Genetic engineering and synthetic immunology to

create intelligent cells that integrate environmental cues for decision making,

3)  Protein  engineering  to  develop  safe  and  potent  immune-modulatory

proteins and nanostructures with desired trafficking profile, release kinetics,

enhanced or novel functions.  

The prospective candidate will be exposed to a variety of research topics and

engage in diverse experiments that utilize molecular biology and immunology

techniques as well as animal models. The candidate will have an opportunity

to work on a project that aims to develop a new CAR T cell therapy for solid

tumors and will also assist in daily lab organization and operations. There will

be opportunities to explore and lead an independent research direction.

Required Education, Experience, and Skills

1. A  minimum  of  a  Bachelor’s  degree  (or  equivalent)  is  required,

preferably in biomedical sciences, bioengineering, or chemistry.

2. The ideal candidate will be a team player, highly self-motivated, and

enthusiastic about problem-solving and scientific discovery.

3. Prior lab experience in tissue culture and/or molecular biology work is

preferred. 

4. Experience with lab animal handling is a plus.

5. We  are  looking  for  candidates with  a  minimum  of  two  years  of

availability. The positions are set to begin in the first half of 2025.

Research environment

UPenn/CHOP  is  featured  by  its  unique  geographical  unity,  where  a  top-

ranking medical school, engineering school, and research hospital are closely

connected on a single campus, fostering tremendous opportunities for cross-

departmental collaboration and interdisciplinary research. UPenn/CHOP is

an international leader in cell and gene therapy research and has established

state-of-the-art  GMP  facilities  for  viral  vector  and  therapeutic  cell

manufacturing. The Ma lab is a member of the Abramson Cancer Center, the

Center for Cellular Immunotherapy, Institute for Translational Medicine and

Therapeutics,  and  the  Raymond  G.  Perelman  Center  for  Cellular  and

Molecular  Therapeutics.  Here,  we  are  perfectly  positioned  to  bring  our

research from bench to bedside at an unprecedented pace. 

Successful  candidates  will  benefit  from  the  thriving  and  collegial

UPenn/CHOP  research  community,  tailored  career  development  guidance,

state-of-the-art research facilities, and an excellent benefits package.

Applicants  should  send  their  inquiries  to  Dr.  Tomasz  Grzywa

(grzywat@chop.edu) along with a CV or apply directly through Linkedin. 

Happy to answer questions, feel free to email me.