What are the responsibilities and job description for the Principal Scientist, Computational Chemistry position at Merck Sharp & Dohme?
Job Description
Position Description
We are seeking a creative, self-motivated computational chemist with exceptional interpersonal and problem-solving skills to join the Modeling and Informatics (M&I) department in Boston, MA, US. M&I is a diverse and inclusive team of approximately 50 computational chemists, cheminformaticians, data scientists and machine learning specialists who employ state of the art capabilities to drive drug design. We are an integral arm of both discovery and process chemistry and collaborate seamlessly with teams across the globe to innovate and invent better molecules faster. We are looking for a strategic thinker and accomplished computational drug hunter to take on a position that carries significant influence across our Company chemistry from target identification through delivery of clinical candidates.
Key responsibilities will include :
Scientific Innovation :
Leading and defining the in-silico strategy on multiple interdisciplinary discovery projects, design and optimize compounds using advanced computational techniques.
- Analyzing novel drug targets for tractability using drugability assessment, prioritize targets and help define screening and modality strategies.
- Functioning as a subject matter champion for ligand- and structure-based drug design across discovery teams.
- Advancing our modeling capabilities through invention, implementation and application of new methodologies.
Strategy :
Leading strategic efforts to enable our future vision for Modeling and Informatics in chemistry.
Building Relationships :
Mentorship and scientific development of M&I staff both locally and across our network.
We recognize that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of scientists to drive our core mission.
Education Minimum Requirement :
Required Experience and Skills :
Preferred Experience and Skills :
Employee Status : Regular
Relocation : Domestic
VISA Sponsorship :
Travel Requirements :
Shift :
Not Indicated
Hazardous Material(s) :
n / a
Required Skills :
Data Science, High Performance Computing (HPC), Machine Learning, Researching, Scientific Modeling
Preferred Skills :
Job Posting End Date :
02 / 7 / 2025
Requisition ID : R331775
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