What are the responsibilities and job description for the Analytical Scientist I / II – Lipid Nanoparticles and Biotherapeutics (6-Month Temporary Position) position at ModeX Therapeutics Inc .?
Company Overview
ModeX Therapeutics, an OPKO Health subsidiary, is a clinical-stage biopharmaceutical company developing next-generation multispecific antibodies and vaccines for cancer and infectious disease. ModeX's modular antibody platforms unite the power of multiple biologic components in a single molecule to create multispecific antibodies with greater versatility and potency to fight complex diseases more effectively than traditional approaches. Our current pipeline includes immuno-oncology candidates against both solid and hematological tumors as well as medicines and vaccines for several of the world's most pressing viral threats. Our founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients.
External Description
We are seeking a skilled Analytical Scientist with expertise in the development and characterization of lipid nanoparticles (LNPs), mRNA-based therapies, and conjugated antibodies. The ideal candidate will bring a robust background in lipid analysis, advanced analytical techniques, and hands-on experience with state-of-the-art laboratory tools and platforms.
Key Responsibilities:
- Perform analytical characterization of conjugated and unconjugated Abs, mRNA, mRNA-lipid moieties and lipid-based drug delivery products. Conduct quantitative analysis using advanced instrumentation.
- Operate and troubleshoot HPLC / UPLC systems, including those equipped with Charged Aerosol Detection (HPLC-CAD)
- Utilize Agilent's Open Lab software for data acquisition, processing, and reporting
- Analyze and interpret data to assess quality, purity, and stability of therapeutic formulations
- Perform accurate data integration and recording
- Work closely with cross-functional teams to support drug discovery and CMC development programs
- Utilize e-lab notebook to record procedures and upload results
- Summarize and present the data in group meetings
Qualifications and Skills:
- Minimum of 2-3 years in analytical development with a focus on LNPs, mRNA, or conjugated antibody therapeutics
- PhD preferred, relevant life science discipline
- Proficiency in lipid analysis and characterization techniques
- Hands-on experience with HPLC-CAD and Agilent’s Open Lab software
- Strong expertise in the characterization of LNPs, lipids and antibody conjugates
- Excellent problem-solving and critical-thinking skills
- Strong written and verbal communication skills, with a commitment to detail and accuracy
ModeX Therapeutics is an Equal Opportunity Employer
