UNIV - Staff Scientist II - Department of Pharmacology

Job Description Summary

The Paczesny laboratory is seeking highly motivated candidates for a Senior Scientist (SSII) studying tumor immunology including hematopoietic cell transplantation to treat myeloid malignancies. The major interests of the lab are discovering and validating new biomarkers and immune cells subsets in tumor immunology, generating, and testing in vivo the efficacy of bispecific/trispecific antibodies, generating new cell-based immunotherapies, as well as developing new mechanistic allogeneic and syngeneic in vivo immune models. In this position, you will have the opportunity to develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems. You will also gain extensive experience and training in hematopoietic cell transplantation biology, acute myeloid malignancies, and pre-clinical study development. The candidate will be expected to have 7 years of experience in immunology.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type

Research Grant

Cost Center

CC001032 COM PHARM Administration CC

Pay Rate Type

Salary

Pay Grade

University-00

Pay Range

0.00 - 0.00 - 0.000

Scheduled Weekly Hours

40

Work Shift

Job Description

The Paczesny laboratory is seeking highly motivated candidates for a Senior Scientist (SSII) studying tumor immunology including hematopoietic cell transplantation to treat myeloid malignancies. The major interests of the lab are discovering and validating new biomarkers and immune cells subsets in tumor immunology, generating, and testing in vivo the efficacy of bispecific/trispecific antibodies, generating new cell-based immunotherapies, as well as developing new mechanistic allogeneic and syngeneic in vivo immune models. In this position, you will have the opportunity to develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems. You will also gain extensive experience and training in hematopoietic cell transplantation biology, acute myeloid malignancies, and pre-clinical study development. The candidate will be expected to have 7 years of experience in immunology.

Job Duties:

35% - Develop and lead projects using several cutting-edge in vivo models including hematopoietic cell transplantation and novel xenograft in vivo systems. Each project leading to a presentation at a national meeting as well as manuscript of impact factor > 10. (Crucial)

35% - Identify, propose, and lead novel research experiments weekly while been able to resolve problems and find diverse alternative experiments. Each experiment leading to interpretable tangible weekly data leading to figures/ Table for a manuscript. (Crucial)

25% - Train in hematopoietic cell transplantation biology, and pre-clinical study development building on an already established extensive experience directing resolution of novel and diverse problems in immunology. Similarly, the outcomes will lead to a publishable manuscript - (Essential)

5% - Perform other essential duties as requested. These will include maintain animal colonies, collaborate with DLAR to provide the best animal care, update IACUC and IBC protocols, order supplies for the laboratory. - (Essential)

MUSC Minimum Training and Experience:

A Ph.D., M.D. or equivalent with two years postdoctorate experience plus evidence of scholarly activity as demonstrated by at least five first author publications.

MUSC Physical Requirements:

(Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift)

Ability to perform job functions in an upright position. (Continuous)
Ability to perform job functions in a seated position. (Continuous)
Ability to perform job functions while walking/mobile. (Frequent)
Ability to climb stairs. (Infrequent)
Ability to work indoors. (Continuous)
Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent)
Ability to bend at the waist. (Frequent)
Ability to twist at the waist. (Frequent)
Ability to perform 'pinching' operations. (Continuous)
Ability to fully use both hands/arms. (Continuous)
Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous)
Ability to fully use both legs. (Continuous)
Ability to reach in all directions. (Continuous)
Possess good finger dexterity. (Continuous)
Ability to maintain tactile sensory functions. (Continuous)
Ability to maintain good olfactory sensory function. (Continuous)
Ability to lift and carry 30 lbs., unassisted. (Frequent)
Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent)
Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent)
Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent)
Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent)
Ability to maintain 20/40 vision, corrected. (Continuous)
Ability to see and recognize objects close at hand. (Continuous)
Ability to see and recognize objects at a distance. (Continuous)
Ability to match or discriminate between colors. (Continuous)
Ability to determine distance/relationship between objects; depth perception. (Continuous)
Good peripheral vision capabilities. (Continuous)
Ability to maintain hearing acuity, with correction. (Continuous)
Must be ambidextrous.
Ability to perform gross motor functions with frequent fine motor movements. (Continuous)
Ability to be qualified physically (by medical personnel) for respirator use, initially and annually.
Ability to work alone in isolated areas, such as darkrooms. (Frequent)

Application materials should be addressed to:

Sophie Paczesny, MD, Ph.D.

Professor of Immunology and Pediatrics

Co-Leader Cancer Biology and Immunology Program

Sally Abney Rose Endowed Chair in Cancer Stem Cell Biology

Medical University of South Carolina

Hollings Cancer Center

86 Jonathan Lucas, Rm HO612E

Charleston, SC 29425

843-792-1034

paczesns@musc.edu

Additional Job Description

Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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