What are the responsibilities and job description for the TEMP - Associate Scientist / Scientist, In Vivo Pharmacology position at Neurocrine Bioscience?
Who We Are:
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do:
Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company’s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson’s disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About the Role:
Employed through a preferred contingent supplier to support projects on-site or off-site for neurocrine.
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Your Contributions (include, but are not limited to):
- Independently execute in vivo PK/PD and/or efficacy studies that support nonclinical and clinical stage programs in the neurology and endocrinology disease space
- Administer small molecule compounds and biologics to naïve and disease-model rodents (mouse and rat), measure endpoints (body weight, clinical scores, behavioral) and collect biospecimens
- Follow study protocol, IACUC protocols, SOP and animal welfare policy in animal studies. Help maintain laboratory and supply inventories
- Have effective troubleshooting, problem-solving and communication skills
- Work both independently and collaboratively. Candidates must be flexible and have strong multitasking skills
- Collect, organize, and present scientific/technical data internally and in project team meetings
- Perform all duties in keeping with the Company’s core values, policies and all applicable regulations
- Performs assigned experiments to support scientific activities and project goals involving in vivo pharmacology assessment of novel therapeutics
- May design less complex experiments
- Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions to problems
- Works with stereotaxic surgical techniques
- Oversees compound dosing via multiple routes of administration
- Responsible for behavioral assay development, validation and screening
- Completes data analysis and reporting. Maintains and updates SOP’s and writes data summaries for experiments conducted
- Handles and doses animals in a laboratory setting
- Reviews, comprehends and complies with all SOP’s, IACUC procedures, and safety and quality assurance standards at all times
- Provides training and/or supervision to junior staff, as needed
- Other duties as assigned
Requirements:
- BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and 2 years of experience in the handling and dosing of rodents in a laboratory setting OR
- MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred
- Compound administration different routes (PO IP SC IM)
- Previous experience with stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding is a plus
- Extensive hands-on knowledge of behavioral testing in a variety of assays like locomotor activity, fear conditioning
- Occasional weekend work required
- Recognizes fundamental anomalies in data points and identifies issues in experiments/processes
- Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
- Strong knowledge of one scientific discipline
- Good knowledge of scientific principles, methods and techniques
- Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
- Strong computer skills
- Good communications, problem-solving, analytical thinking skills
- Ability to meet deadlines
- Good project management skills
- High level of organization and attention to detail
- Willingness and ability to work both independently and as part of a team
- Must have working knowledge of Microsoft Office, Word, and Excel
- Advanced multitasking, trouble shooting and deductive reasoning skills required
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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
