Vivo Animal Research Investigator - NCWR

Position Details Req ID : req18251 Position Title : Vivo Animal Research Investigator - NCWR Position Type : Staff Full-Time Position Number : GS9182 OSU Campus : Tulsa - Center for Health Sciences / OSU Medicine Department : Center for Wellness and Recovery Location Address : 1111 West 17th Street Tulsa , Oklahoma, 74107 United States Hiring Supervisor : Hiring Range : (Contingent upon available funding) : Commensurate with education and experience Work Schedule : Typically 8 hrs / day, 5 days / week Faculty Appt Period : Job Summary : THIS POSITION IS GRANT FUNDED. Job Summary : TheNCWR is currently expanding its in vivo research team with openings atall levels. Significant hands-onwork in the animal vivarium is expected from all candidates. For the moresenior levels, strategic and managerial duties are also expected. Additional Responsibilities : -Familiarity and / or willingness to learn and apply specialized techniques such as DREADD, imaging methods, microscopic techniques, etc., to on-going research at the NCWR. -Be willing to learn new behavioral techniques and animal models and apply them independently or as part of a team. -Familiarity with software related to behavioral testing and data collection. -Attention to detail in record-keeping and lab safety including the use of controlled substances in experiments. The National Center for Wellness and Recovery(NCWR) at Oklahoma State University Center for Health Sciences (OSU-CHS) waspublicly launched in 2017 with a mission to inspire hope for people sufferingwith chronic pain and substance use disorders through treatment and research.The NCWR was the recipient of nearly $200M from Purdue Pharma as part of theirsettlement with Oklahoma and the funds are being leveraged to advance thescience of addiction and pain. Currentlywe are making multi-million-dollar investments in neuroscience research anddrug discovery competencies including medicinal chemistry, molecular biology,animal models, and pharmacology. We are uniquely organized within OSU-CHS toallow researchers to be highly focused on the urgent mission of the NCWR as apriority. NCWR researchers and clinicians are expected to seek ways to rapidlytranslate new mechanism-based treatment modalities to patient care. The NCWR iscurrently building a $21M state-of-the-art animal facility, as well as a $50M, 30,000sq ft pharmaceutical research facility as part of a new medical district in downtownTulsa. The NCWR endorses a culture of teaching, learning, and collaboration,thus creating opportunities for our people to grow in their careers throughdirect interactions on multidisciplinary teams with colleagues. This is an opportunity to join a growing teamthat is focused on making a positive impact in the lives of those sufferingfrom addiction and / or chronic pain. Environmental Hazard : Possible exposure to hazardous material, hot and cold, blood borne pathogens.Exposure to rodents. Physical Requirement : Ability to lift and carry 20 pounds, stoop, reach, stand, walk, finger, grasp,feel, talk, hear, see, and perform repetitive motions with or withoutreasonable accommodations. Special Instructions to Applicants Education & Experience Position Qualifications : Requirements : -Bachelors, Masters, or a PhD in Neuroscience, Pharmacology, or related field. -In vivo animal research experience is required. -Experience may include post-doctoral, academic and industry working in an animal laboratory -A broad knowledge of animal anatomy,physiology, and biochemistry to help develop and support in vivo models toscreen therapeutics and devices being developed for various clinicalindications. Skills, Proficiencies, and Knowledge : -Experience in pre-clinical rodent models, for example, substance use disorders and pain, models of behavior including CPP, and anxiety, as well as physiological measures including respiration and GI motility. -Excellent understanding of IACUC-related concepts and will be familiar in AAALAC standards for laboratory animal care and use. -Design and perform experimental models related to pain and addiction behavior in rodents, including preparation of protocols and IACUC interactions. -Provide input into new equipment purchases, set-up, and training as needed, necessary for NCWR to have a superior level of capabilities that support state-of the-art and flexible in vivo operations in neuroscience with emphasis on pain and addiction. -Maintain the cleanliness and readiness of the equipment used by NCWR in the vivarium as needed. -As needed, develop and validate behavioral models and methods that support NCWR’s multidisciplinary research projects and exploratory research. This may include modification of known literature procedures or developing novel techniques. -Interact within multi-disciplinary research teams to establish screening tree criteria and test novel compounds in appropriate animal models for efficacy and side effects. Various methods of dosing will be required. -Collaborate with NCWR analytical scientists to develop and apply in vivo pharmacokinetics and pharmacodynamics techniques. This will include blood spot analysis, dosing, time-dependent blood sampling, and analysis. -Write grant proposals, present at internal meetings, plan budgets, and supply technical content to patent applications and other documents. -Supervise staff as needed, including PhDs and non-PhDs, including goal setting, mentoring, and allocating resources. Preferred : -Operational and interpretational knowledge of multiple animal models and equipment is highly preferred. -Grant, publication, and report-writing experience. -Industrial Experience. -Experience in rodent behavior, dosing, sampling, documentation and report writing, PK / mass balance studies, as well as protocol reading and writing as needed. -Experience with laboratory animal surgery and post-operative care, veterinary staff consultation, cursory necropsy and euthanasia.