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Senior Research Associate, Vector Engineering.

Oxford Biomedica
Bedford, MA Full Time
POSTED ON 1/28/2025
AVAILABLE BEFORE 4/28/2025

We use science to save lives, and so can you (change this)

We are looking to recruit a Senior Research Associate to join the Vector Engineering team. The objective of the role will be to focus on the development of plasmids to facilitate improved AAV manufacturing.

The Vector Engineering team focuses on understanding AAV biology to improve productivity and drug quality during viral vector manufacturing through plasmid design. As an innovation-driven CDMO, we also support vector genome and plasmid design for clients, enhancing the production of materials to support their preclinical programs and facilitating the advancement of life-changing viral vector therapeutics into clinical development.

This Bedford, MA based position is an exciting opportunity to shape the strategic direction of Viral Vector downstream process development within a dynamic CDMO environment.

Your responsibilities in this role would be :

  • Support the design and execution experiments aimed at improving AAV productivity and product quality using a suspension cell platform
  • Clone and characterize plasmids used in vector production
  • Develop and perform of a variety of molecular biology assays including PCR, qPCR, gel electrophoresis, SDS-PAGE / Western blotting, molecular cloning etc.
  • Organize and maintain plasmid stock inventory and liaise with upstream process development to facilitate transfer of plasmids as needed
  • Maintain appropriate production protocols and analytical results in company databases and electronic lab notebooks and author technical reports as needed

We are looking for :

  • BS / MS or equivalent with 2-5 years of industrial / academic laboratory experience in a relevant field
  • Experience with cell culture and molecular biology techniques
  • Experience with flow cytometry experiments and analysis is considered an asset
  • Effectively manage and prioritize multiple parallel laboratory activities
  • Independently motivated, detail oriented, organized and good problem-solving ability
  • Excellent interpersonal written and oral communication skills
  • About Us :

    OXB is a quality and innovation-led viral vector CDMO (Contract Development and Manufacturing Organization) with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

    OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus, and adenoviral vectors. Oxford Biomedica’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise

    What’s in it for you :

  • Competitive reward packages
  • Development opportunities
  • Welcoming, friendly, supportive colleagues
  • A diverse and inclusive working environment
  • State of the art laboratory and manufacturing facilities
  • We want you to feel inspired every day. We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and teamwork, and so can you.

    At OXB (US) LLC we are committed to providing equal opportunity to all employees and applicants. Our policy is to recruit, hire, train, and reward employees for their individual abilities, achievements and experience without regard to race, color, religion, sexual orientation, age, national origin, disability, marital or military status.

    This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.

    Collaborate. Contribute. Change lives

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