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Research Assistant / Senior Research Assistant

Pallando Therapeutics
San Carlos, CA Full Time
POSTED ON 3/30/2025
AVAILABLE BEFORE 4/30/2025

Company Description

Pallando Therapeutics is pioneering the development of tissue-sparing protein degraders, a transformative approach in targeted therapeutics. We have recently closed an oversubscribed financing round backed by a distinguished group of leading investors.

Job Title : Research Associate / Senior Research Associate, Biology

Job Summary :

We are seeking a highly motivated and skilled Research Associate (RA) or Senior Research Associate (SRA) with extensive experience in mammalian cell culture and cell-based assays. The successful candidate will play a key role in supporting our drug discovery and development programs by executing and optimizing in vitro assays to evaluate target biology and therapeutic candidates.

Key Responsibilities :

  • Perform routine and advanced mammalian cell culture techniques, including maintenance, expansion, and cryopreservation of cell lines (adherent and suspension)
  • Develop, optimize, and execute cell-based assays (e.g., viability, proliferation, apoptosis, cytotoxicity, reporter gene, and functional assays) to support drug screening and mechanism-of-action studies
  • Utilize techniques such as immunocytochemistry, ELISA, Western blotting, and high-content imaging to analyze cellular responses
  • Maintain accurate records of experimental procedures and results in electronic lab notebooks (ELNs) and prepare detailed technical reports
  • Present findings to internal stakeholders and participate in team meetings to provide scientific input
  • Ensure compliance with laboratory safety protocols and best practices in cell culture and assay development

Required Qualifications :

  • Proven expertise in mammalian cell culture techniques, including handling a variety of cell lines and primary cells
  • Hands-on experience with cell-based assay development and optimization (e.g., luminescence, fluorescence, colorimetric assays)
  • Proficiency in utilizing laboratory instrumentation such as plate readers
  • Familiarity with molecular biology techniques such as Western blotting, and transfection methods
  • Preferred Qualifications :

  • Prior industry experience in a biotech or pharmaceutical setting
  • Familiarity with data analysis tools such as GraphPad Prism, or image analysis software
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