Senior Associate Scientist (non-PhD), Cell Pharmacology

Use Your Power for Purpose

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist, you will be at the forefront of our mission, contributing to the development of innovative therapies that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting-edge technologies to make a tangible impact on global health. Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top-tier medicines to patients worldwide.

Description

Pfizer Oncology Research & Development (ORD) is seeking a Senior Associate Scientist (non-PhD) to join our Cell Biochemistry group within Discovery Technologies. The candidate will join our interdisciplinary and highly collaborative team to support and advance our preclinical oncology drug pipeline. The ideal candidate will have a strong background in cellular and molecular biology, in vitro pharmacology, and biochemical/cell assay development. They will design, plan, and execute studies to explore novel drug targets. They will implement new technologies to support drug discovery, interpret experimental results, and present their research. The successful candidate will have a proven track record of independent research experience with an ability to learn quickly and think critically. This position will provide the motivated candidate with ample opportunity for scientific growth through exposure to all aspects of the drug discovery process. Special consideration will be given for candidates that have expertise in cancer biology.

Role responsibilities

• Develop and validate relevant cell assay systems to screen and characterize small molecules in medium and high-throughput formats.

• Design, execute, analyze, and interpret experiments to drive SAR.

• Design, plan, and execute studies to explore the mechanism of action of novel drug targets and understand related biology and biomarker responses.

• Clearly communicate results and methodologies to teams and appropriately document in laboratory notebooks.

• Keep current with appropriate biology and technical literature.

• Contribute new ideas to advance project work.

• Contribute to a culture that prioritizes scientific discovery, pursues excellence, and encourages growth.

Here Is What You Need (Minimum Requirements)

• BS or BS/MS in the biological sciences with 2-5 years of relevant laboratory experience.

• Extensive cell culture experience required.

• Demonstrated success in cellular assay design and development such as HiBiT, Nanoluciferase, NanoBRET, ELISA, thermo-shift, CETSA, Alpha-Screen, HTRF, etc.

• Experience in cellular and molecular biology techniques such as western blotting, qPCR, CRISPR-Cas9 or si/shRNA, immunofluorescence, immunoprecipitation, cloning/plasmid engineering, etc.

• Ability to work independently and design experiments that test complex hypotheses.

• Attention to detail, and ability to multi-task/ prioritize and manage timing of daily activities.

• Effective oral and written communication skills.

• Ability to work well as part of an interdisciplinary team.

• Fluency in basic data analysis software such as GraphPad, Excel, Activity Base, etc.

Additional Qualifications (Preferred Requirements)

• Pharmaceutical industry experience.

• Experience in generation and/or interpretation of multi-omic datasets, such as RNAseq, ChIPseq, proteomics, or functional genomic screens.

• Preference for candidates with expertise in oncogenic signaling, cell cycle regulation, and/or epigenetic/transcriptional regulation.

PHYSICAL/MENTAL REQUIREMENTS

Basic job will require both work at the lab bench and analysis time at the computer.

Additional Information:

• Work Location Assignment: On Premise
• Last Day to Apply: January 31, 2025

The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

Employment Type: Full time

Salary : $66,500 - $110,900