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Senior Research Associate, Cell Biology

Pioneering Medicines
Cambridge, MA Full Time
POSTED ON 2/5/2025
AVAILABLE BEFORE 3/6/2025
Company Summary

FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary

We are seeking a motivated (Senior) Research Associate to join our Cell Biology team and have a significant role in our efforts characterizing nucleic acid function and responses in primary immune cells, which emphasis on T cell biology. This individual will focus on hands-on laboratory benchwork, brings thoroughness and attention to detail to their work, and is curious and willing to learn. The candidate will have the opportunity to work alongside a highly collaborative team in a fast-paced environment.

Key Responsibilities

  • Culture and maintenance of cell lines and primary immune cells
  • Execute, troubleshoot and analyze data from nucleic acid function assays on immune cells
  • Share experimental methods and data effectively in both oral and written formats and maintain excellent record keeping
  • Work in multiple projects simultaneously and pivot on experimental priorities as required to align with company goals.
  • Comfortable working both as independent contributor and as part of a collaborative, multidisciplinary team.

Qualifications

  • BS or MS degree in Biology, Immunology, Virology, or related field
  • Minimum 2 years of experience handling cell lines and primary cell lines is required
  • Experience with experimental design and hands-on execution of in vitro assays to profile nucleic acid function (multi-color flow cytometry, Incucyte-based imaging, luciferase assays, microscopy, qPCR) is required
  • Experience with nucleic acid delivery methods (transfection, nucleofection, electroporation)
  • Highly motivated to execute at the bench and bring strong organizational and problem-solving skills
  • Strong communication and interpersonal skills
  • Meticulous attention to detail and enthusiasm towards developing new skills
  • Ability to adapt, execute and thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment

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