What are the responsibilities and job description for the Sr. RA, In Vivo Pharmacology position at Planet Pharma?
6 month contract
SSF, CA
Duties:
KEY ROLE AND RESPONSIBILITIES:
- Proficient in basic animal handling, including blood sample collection and necropsy with organ/tumor sample collection.
- Setup and execution of in vivo studies using xenograft and syngeneic mouse models of solid tumors including animal preparation/surgery, tumor implantation (s.c., i.p., i.v., or orthotopic), preparation and dosing of therapeutic T cells and other agents via various routes of administration, tracking of tumor growth (eg., bioluminescence/fluorescence, micro-CT, and caliper measurements), collection of blood, tissue, tumor samples, and monitoring of animal health.
- Maintenance of a highly functioning in vivo and ex vivo labs, working with the other members of the In Vivo Pharmacology group and other cross-functional scientists.
- Ex vivo study responsibilities include cell culture, collection and processing of organs and tumor samples for immunological and pathological analysis.
- Collection, entry, analysis, and presentation of study data to project teams
- Generation and maintenance of electronic lab notebook (ELN) reports, including basic statistical data analysis.
PREFERRED EDUCATION:
- BSc. in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 7 years’ experience within the area of focus; or
- MSc. in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 5 years’ experience within the area of focus;
PREFERRED EXPERIENCE:
- Proficient in executing various xenograft and syngeneic tumor models using immunocompromised (NSG-MHCI/II-dKO) and immune-competent mice with adoptive T cell transfer
- Proficient with mammalian cell culture techniques such as cell line passaging, cryopreservation and cell thawing, and cell counting.
- Proficient using and analyzing high-parameter flow cytometry
KNOWLEDGE, SKILLS AND ABILITIES:
- Data analysis using software packages (FlowJo, FCS Express, Prism)
- Experience using and analyzing common immunology and oncology related to the specific project; cell therapy experience is ideal, more complex experience a plus
- Proficient in sterile tissue culture technique and experience working with human cells
- Experience with flow cytometry assays and analysis; more complex analysis and cell sorting experience a plus
- Experience in data production and reporting for IND-enabling studies
- Additional specific experience related to the area of focus may be required
Pay Rate Range: $50-64/hr depending on experience
Salary : $50 - $64
