Scientist

Overview

We are seeking a highly motivated scientist to support NGS-based liquid biopsy assay development. As a member of the Oncology R&D team, this role will collaborate with lab members and staff from cross-functional team to develop, validate and commercialize oncology assays. Activities may be focused on individual projects or assignments as a member of a project team which may include project leadership duties.

Responsibilities

• Perform laboratory experiments following defined protocols and company procedures. Wet lab tasks include DNA/cfDNA extraction, NGS library preparation, target enrichment, and Illumina-based NGS sequencing.
• Under the direction of the Scientific Director, report status of assigned projects through the preparation of detailed reports and documentation that summarize experiment results.
• Ensure compliance with regulatory and quality standards for assay development under design control.
• Work within established parameters on individual assignments, on project teams for longer-term projects and as a technical leader to Assistant Scientists or Associate Scientists.
• Identify problems, investigate alternatives and recommend possible courses of action.
• Maintain knowledge of technological developments that may assist in the completion of an assignment or lead to new products, processes or procedures by reading current literature.
• Effectively utilize and apply advanced methods or technologies.
• Contribute ideas for new product development typically within existing markets.
• Responsibilities include supporting and complying with the company hazard waste handling practices and other safety procedures and protocols.
• Other duties as assigned. This is not an exhaustive list of all duties and responsibilities, but rather a general description of work performed by the position.

Qualifications

Required Work Experience:

• Requires at least 6 (six) years of extensive industrial experience and significant demonstration of capabilities for a candidate with a Bachelor's degree or at least 4 (four) years of relevant industrial experience with a Master's degree, or a Ph.D. with thesis.

Preferred Work Experience:

• Experience with liquid handling robots, sequencers, or similar complex equipment.
• Prior experience in liquid biopsy oncology assay development is preferred.
• Familiarity with regulatory and quality standards for diagnostic assay development (e.g., CAP/CLIA, FDA IVD) is a plus.
• Ability to work collaboratively in a fast-paced. Cross-functional environment.

Physical and Mental Requirements:

• Frequently required to use hands to finger, handle or feel objects, tools or controls, and reach with hands and arms in the operation of equipment or instruments located in the work environment.
• Frequently required to sit and stand; and is occasionally required to walk and stoop.
• Frequently lift and/or move up to 10 pounds and occasionally lift and/or move up to 25 pounds.
• Specific vision abilities required by this job include close vision and depth perception.

Knowledge:

• Knowledgeable in the use of common laboratory equipment and safe chemical handling. Requires a thorough knowledge of related products and technologies gained through developmental experience in an academic or industrial setting.

Skills:

• Ability to read and interpret documents such as professional journals, operating instructions, and procedure manuals.
• Ability to write complete reports and correspondence.
• Ability to speak effectively in one-on-one and small group situations.
• Ability to apply mathematical concepts to problem-solving situations.
• Ability to apply mathematical operations to such tasks as frequency distribution, determination of test reliability and validity, analysis of variance and correlation techniques.
• Ability to apply commonsense understanding to carry out instructions furnished in written, oral, or diagram form.
• Ability to deal with problems involving several variables in a variety of situations.

EEO

Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets