What are the responsibilities and job description for the Associate Engineer, Gene Therapy Pilot Purification position at Sarepta Therapeutics?
Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
Physical and Emotional Wellness
Financial Wellness
Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
The Associate Engineer will drive the development of Sarepta's Gene Therapy platform within the Pilot team. They will be primarily responsible for assisting the Pilot team in downstream operations, providing support in the installation and operation of downstream production equipment. The Associate Engineer will support scale-up studies and material production campaigns within Sarepta's internal laboratories. They will also provide production support of cell culture and solution preparation operations and complete associated process documentation. The Associate Engineer will be expected to work in close collaboration with other Pilot Team members, as well as colleagues in development and manufacturing organizations.The Opportunity to Make a Difference
- Fostering a team environment. Contributing to a safe, efficient and effective lab environment with personal accountability.
- Following downstream batch records and executing purification operations to include: Column Packing, Filtration, Chromatography, and UF/DF.
- Troubleshooting scientific and technical challenges and contributing to their resolution.
- Collecting and performing basic analysis of production and experimental data.
- Performing production operations in other functional areas as part of a cross functional pilot team to include:
- Preparing and filtering media and buffer solutions according to standard procedures and solution preparation records.
- Constructing and sterilizing tubing assemblies according to assembly descriptions.
- Performing cell culture operations to include suspension culture passaging, bioreactors operations and harvest.
- Following and completing all documentation to include operating instructions, procedures, solution preparation records and tubing assembly descriptions.
More about You
- B.S. in a scientific field with 0-2 years of related experience or A.S. in a scientific field with 2 years of related experience. Candidates with additional qualifications and related experience will be considered.
- Experience in purification operations such as filtration, chromatography and UF/DF is highly desirable.
- A good understanding of drug substance manufacturing principles and unit operations.
- Familiarity with common lab equipment and supplies required.
- Excellent communication, organization, and planning skills with a history of meeting team objectives and timelines.
- Interpersonal skills that promote collaboration and relationship-building across various drug discovery and development functions.
- Ability to troubleshoot and solve technical issues.
- Execution-focused, team oriented, highly motivated with a dependable work ethic.
- Willingness to work in a fast-paced, dynamic and innovative environment.
- Able to perform rotational weekend work.
- Ability to lift and carry 50 lbs is a necessity.
What Now?
We're always looking for solution-oriented, critical thinkers.
So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
Salary : $60,000 - $75,000
