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Gene Therapy Upstream Process Development Co-op

Sarepta Therapeutics
Burlington, MA Full Time
POSTED ON 3/29/2025
AVAILABLE BEFORE 5/28/2025

Why Sarepta? Why Now?

The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.

We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.

What Sarepta Offers

At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity.

The Importance of the Role

Sarepta Therapeutics is seeking a motivated individual to assist in the upstream process development to advance Sarepta's Gene Therapy platform to treat rare diseases. The co-op will support the development and optimization of robust, well-characterized, high-quality and high-yielding cell culture processes for viral vector production. Additionally, the co-op will contribute to the understanding and development of emerging upstream technologies for future viral vector production. This role offers the opportunity to gain valuable knowledge of process workflows and stay at the forefront of the current viral vector production industry.

The Opportunity to Make a Difference

This application is for a 6-month co-op program that will start on July 7th, 2025, and conclude on December 19th, 2025. This is a full-time, 40 hours a week, co-op program.

  • Assist in the design and execution of upstream process development studies, including cell passaging, cell counting, media preparations, monitoring metabolites and media components, and operating and sampling of bioreactors.

  • Support innovative projects to improve productivity, including the development of advanced upstream cell culture technologies, media/feed development and the evaluation of new cell lines.

  • Collaborate with teams of scientists in the areas of molecular biology, downstream process development, and process analytics.

  • Adhere to company and department SOPs on lab operations and good documentation practice, and EHS lab safety regulations with highest standards.

  • Support data collection, analysis and visualization and presents data in project team and departmental meetings.

More about You

  • Undergraduate (junior or senior) or graduate student in life sciences, bioengineering, chemical engineering or related fields.

  • Hands-on experience with aseptic techniques for cell culture is highly desired.

  • Knowledge of cell culture processes pertinent to viral vector production and bioreactor operation is a plus.

  • Strong work ethic and ability to plan and execute lab work with guided supervision.

  • Some troubleshooting/problem-solving skills; excellent written and verbal communication skills.

  • Detailed-oriented, self-motivated and eager to work in a fast-paced environment.

  • Able to lift up to 25 kg.

What Now?

We're always looking for solution-oriented, critical thinkers.

So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.

#LI-Onsite#LI-MC1

This position requires work on site at one of Sarepta's facilities in the United States.

The targeted salary range for this position is $22 - $34 per hour depending upon years of education completed and nature of role.

Candidates must be authorized to work in the U.S.

Sarepta Therapeutics offers a competitive compensation and benefit package.

Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

 

Salary : $22 - $34

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