What are the responsibilities and job description for the Senior Associate, Analytical Development position at Sarepta Therapeutics?
Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
Physical and Emotional Wellness
Financial Wellness
Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
This role is crucial in supporting all aspects of work related to the cell line development group within the Analytical Development Department at Sarepta. The candidate will interface with R&D, Tech Ops, QCTS, or QC for cell bank related activities or discussions. The ideal candidate will also support MCB/WCB management activities and actively interact with CRO/CDMO. This role is critical for the success of potency analytical strategies and will significantly impact such assays.The Opportunity to Make a Difference
- Hands-on work conducting research cell bank generation and research cell bank release testing
- Managing the logistics and inventory of these research cell banks internally
- Preparing reagents, and cell culture media for routine cell culture. Conducting cell growth studies and cell growth media studies
- Assisting cell line engineering and development of novel cell lines for analytical assays, particularly potency assays
- Assisting in managing laboratory supplies related to cell culture and experiments and taking initiative to organize laboratory space.
- Authoring and reviewing SOP drafts.
- Supporting MCB/WCB generation and related logistics or documentation alongside other scientists in the group.
More about You
- BS/MS degree with 5 years of hands-on laboratory work experience is required.
- Hands-on experience with mammalian cell culture is required, especially adherent cell culture in the pharmaceutical or CRO/CDMO industries.
- Experience with good documentation practices is a must
- Familiarity with routine bench scale cell culture and cell banking procedures is a must.
- Experience with cell culture-related media studies or cell growth studies is beneficial.
- Proficiency in various gene editing techniques is highly desired.
- Willingness to take on new challenges in developing new cell lines for potency assays or mechanism of action studies under the guidance of group scientists.
- Previous experience with both adherent and suspension iPSC culture studies is welcomed.
- Experience in developing analytical assays is preferred.
- Knowledge of ICH guidelines for analytical assay development is a plus.
- Knowledge of GxP regulations related to cell banks is a plus.
- Attention to details, open-minded fast learner willing to learn from everyone in the group and explore new challenges.
What Now?
We're always looking for solution-oriented, critical thinkers.
So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
Salary : $92,000 - $115,000
