What are the responsibilities and job description for the Research Scientist I - Carbone Lab position at Seattle Children's?
Title: Research Scientist I - Tumor Immunology and Lab Operations (Carbone Lab)
Description: We're looking for a Research Scientist I to join our team and help advance our understanding of the tumor immune microenvironment, focusing on dendritic cells (DCs) and their role in cancer immunotherapy. This position offers the opportunity to contribute to high-impact research using innovative tools like the STAMP model (Skin Tumor Array by Micro-poration), which enables non-invasive, high-throughput monitoring of immune cell recruitment and interactions in tumors (PMID: 37258670).
In this role, you will play a central part in ensuring the smooth daily operations of our new and growing lab, while collaborating closely with the Principal Investigator (PI) on groundbreaking research aimed at advancing the future of cancer immunotherapy. This position offers significant opportunities for professional growth, including mentoring new lab members and helping build a strong lab culture.
Job Responsibilities
Bachelor’s Degree in biology, microbiology, immunology, molecular biology or biochemistry. Prior experience in a laboratory setting.
Required Credentials
N/A.
Preferred
Research experience in biochemistry, molecular biology, and tissue culture techniques is highly preferred.
Compensation Range
$25.85 - $38.78 per hour
Salary Information
This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.
Disclaimer for Out of State Applicants
This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors.
Benefits Information
Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website www.seattlechildrens.org/careers/benefits.
About Us
Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE
Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.
In 2022, U.S. News & World Report once again ranked Seattle Children’s among the nation’s best children’s hospitals – for the 30th year in a row. For more than a decade, Seattle Children’s has been nationally ranked in all 10 specialty areas evaluated by U.S. News & World Report. We are honored to be the top-ranked pediatric hospital in Washington and the Pacific Northwest.
As a Magnet designated institution, and classified among America’s best large employers by Forbes, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.
Our Commitment to Diversity
Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.
The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.
Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.
Description: We're looking for a Research Scientist I to join our team and help advance our understanding of the tumor immune microenvironment, focusing on dendritic cells (DCs) and their role in cancer immunotherapy. This position offers the opportunity to contribute to high-impact research using innovative tools like the STAMP model (Skin Tumor Array by Micro-poration), which enables non-invasive, high-throughput monitoring of immune cell recruitment and interactions in tumors (PMID: 37258670).
In this role, you will play a central part in ensuring the smooth daily operations of our new and growing lab, while collaborating closely with the Principal Investigator (PI) on groundbreaking research aimed at advancing the future of cancer immunotherapy. This position offers significant opportunities for professional growth, including mentoring new lab members and helping build a strong lab culture.
Job Responsibilities
- 35% Lab Management: Oversee day-to-day operations, including organization, supply management, equipment maintenance, and regulatory compliance to ensure a well-functioning laboratory.
- 35% Animal Colony Management: Manage a mid-sized mouse colony, including breeding, genotyping, and working with on-site veterinary personnel.
- 30% Experimental Research: Assist in the design, planning, and execution of experiments focused on tumor immunology and immune cell regulation within the tumor microenvironment.
- Data Handling: Contribute to data collection, analysis, and interpretation. Maintain accurate and detailed experimental records, and assist in preparing grants, reports, presentations, and manuscripts for publication.
- Scientific Contribution: Actively participate in lab meetings, provide insights during research discussions, and contribute ideas for new projects.
- Lab Support: Be helpful and step in wherever needed, identify and address issues before they impede research.
- Flow cytometry
- Cell culture
- Tissue harvest and processing
- Advanced Microscopy for live imaging of tumor-immune interactions
- Mouse handling, including in vivo techniques and tumor models
- Managing mouse colony and maintaining mouse census
- Cell engineering and plasmid design
- Computational image analysis (Python, ImageJ, or similar tools for image and data analysis)
- Proficiency in key experimental techniques such as flow cytometry, advanced microscopy, cell culture and/or cell engineering.
- Hands-on experience in tissue processing and immune cell characterization through flow cytometry and in vitro immunoassays.
- Familiarity with preclinical tumor models is highly desirable.
- Experience with data analysis tools (e.g., FlowJo, ImageJ) and basic coding skills (Python or similar programming languages).
- Strong background in tumor immunology, cancer biology, or related fields, with a solid understanding of relevant scientific literature.
Bachelor’s Degree in biology, microbiology, immunology, molecular biology or biochemistry. Prior experience in a laboratory setting.
Required Credentials
N/A.
Preferred
Research experience in biochemistry, molecular biology, and tissue culture techniques is highly preferred.
Compensation Range
$25.85 - $38.78 per hour
Salary Information
This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.
Disclaimer for Out of State Applicants
This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors.
Benefits Information
Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website www.seattlechildrens.org/careers/benefits.
About Us
Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE
Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.
In 2022, U.S. News & World Report once again ranked Seattle Children’s among the nation’s best children’s hospitals – for the 30th year in a row. For more than a decade, Seattle Children’s has been nationally ranked in all 10 specialty areas evaluated by U.S. News & World Report. We are honored to be the top-ranked pediatric hospital in Washington and the Pacific Northwest.
As a Magnet designated institution, and classified among America’s best large employers by Forbes, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.
Our Commitment to Diversity
Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.
The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.
Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.
Salary : $26 - $39
