What are the responsibilities and job description for the Scientist-Cellular Genomics position at System One?
Job Title: Scientist-Cellular Genomics
Location: Cambridge, MA
Type: Contract
Overview
Leading pharmaceutical company looking for an experienced Scientist. Ideal candidates should have 3 years of hands-on experience with immunoprofiling technologies and primary immune cells.
Responsibilities
ORGANIZATIONAL RELATIONSHIPS:
Requirements
EDUCATION AND EXPERIENCE:
TECHNICAL SKILLS REQUIREMENTS:
Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.
Ref: #568-Clinical
Location: Cambridge, MA
Type: Contract
Overview
Leading pharmaceutical company looking for an experienced Scientist. Ideal candidates should have 3 years of hands-on experience with immunoprofiling technologies and primary immune cells.
Responsibilities
- Follow existing lab standard operating procedures to:
- Participate in sample collection of murine and human tissues, including the preparation of tubes, interfacing with in vivo scientists to retrieve samples, isolation of primary immune cells, and standard mammalian cell culture
- Participate in sample preparation of murine and human tissues, including tissue fixation, dissociation, sectioning, and antibody staining
- Generate spatial and single-cell data via a number of commercial workflows, including 10x Genomics and Parse Technologies
- Interpret quality control metrics for spatial, single-cell and cytometry experiments
ORGANIZATIONAL RELATIONSHIPS:
- Reports to a scientific director of the Systems Immunology Lab
- Collaborates with and supports several multi-disciplinary experimental teams on a per-project basis
Requirements
EDUCATION AND EXPERIENCE:
- Masters 3 years of experience in Biology, Immunology, or a related field
- Ph'D 0 yrs experience in Biology, Immunology, or a related field
TECHNICAL SKILLS REQUIREMENTS:
- 3 years of hands-on experience with standard immunoprofiling technologies, including
- Flow Cytometry
- Single-cell library preparation (ideally 10x Genomics or Parse Technology)
- Preparation and loading of Illumina sequencing libraries
- Bonus: generation of spatial transcriptomics data (any technology)
- 3 years of experience with primary immune cells, including
- Primary immune cell isolation
- Maintenace of immune cell lines
- Cell culture and in vitro stimulation of primary immune cells
- Bonus: experience with CRISPR mediated functional genomics, including electroporation of primary immune cells
Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.
Ref: #568-Clinical
