Scientist - Synthetic Organic Chemistry

Work Schedule

Environmental Conditions

Job Description

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100 countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

Key responsibilities:

As an Associate Scientist/ Scientist, you will use powerful technologies to perform high-quality research for key pharmaceutical clients across the industry. Your problem-solving skills are an integral piece in helping PPD accomplish our goal of helping bring life-changing therapies to market. You will join the Synthetic Molecule Process Chemistry team, working onsite at the client location to support pharmaceutical research and development focused on process chemistry and Active Pharmaceutical Ingredient (API) manufacturing campaigns.

• Discover and develop robust chemical processes by conducting experiments to scout synthetic routes and optimize reactions for yield, selectivity, and product purity
• Demonstrate developed synthetic processes at laboratory and kilogram scales to enable timely delivery of early- and mid-phase synthetic molecule development candidates in the client's growing pipeline in accordance with cGMP, ICH and FDA regulations
• Develop crystallization processes to isolate synthetic intermediates and control bulk quality attributes of the API conducive to successful development and formulation
• Make detailed observations, interpret results, and document findings via electronic laboratory notebook, batch records, and milestone development reports
• The ability to learn quickly and ultimately to interact with cross-functional team members and contract manufacturing partners
• A desire to keep current with developments in the field through peer-reviewed journals and other media

Education and Experience:

• Bachelor's degree in lab sciences such as Chemistry, Organic Chemistry or similar
• Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2-4 years’)
• OR Masters degree

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

• Process Chemistry / Synthetic Organic Chemistry background desired
• Publication records desired
• Proficiency in NMR, HPLC, and GC instrumentation
• A strong working knowledge of the latest developments in contemporary chemistry including chemo- and/or bio catalysis/asymmetric transformations, organometallic chemistry as well as experience in heterocyclic chemistry
• Ability to understand and independently apply GMP and/or GLP principles in documentation and instrument use
• Proficiency in Microsoft Excel and Word for data analysis and documentation
• Ability to independently optimize chemical reactions
• Strong written and oral communication skills
• Effective time management and project management skills
• Problem solving and troubleshooting abilities

Working Environment:

Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with

proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Benefits

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

Compensation and Benefits

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards