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Postdoc Research Associate - College of Pharmacy - Pharmaceutical Sciences - Thomas Lab

uic
Chicago, IL Full Time
POSTED ON 1/8/2025
AVAILABLE BEFORE 3/8/2025
An NIH-funded Postdoctoral Research Associate position is available in the laboratory of Dr. Douglas Thomas at the University of Illinois Chicago. This position is open immediately to investigate redox-based mechanisms of epigenetic regulation in diseases.

The Thomas Lab focuses on exploring novel mechanisms of epigenetic gene regulation through a combination of biochemistry, cell biology, and genomics approaches. Our research employs both in vitro and in vivo models, integrating advanced methodologies such as mass spectrometry, confocal microscopy, electron paramagnetic resonance imaging of free radicals, chemiluminescence, electrochemical analyses, genomic, and molecular biology techniques.

Notably, we have identified the free radical signaling molecule nitric oxide (NO) as an endogenous regulator of epigenetics, capable of influencing mRNA, histone, and DNA methylation. Current projects emphasize genome-wide analyses of epigenetic events contributing to the development and treatment of epigenetic-driven diseases. These projects build on our recent work, including studies on mRNA methylation (2023) and DNA methylation (2025.

We are seeking a self-motivated, career-oriented postdoctoral researcher to explore the function and dynamic regulation of mRNA and DNA methylation. The position offers a vibrant research environment and dedicated mentoring to support your scientific and professional growth.  



Duties & Responsibilities

  • Responsibilities include, but are not limited to:
  • Cell culture studies.
  • Cell free, kinetic and structural studies.
  • DNA/mRNA Sequencing
  • Mentoring graduate students.
  • Manuscript and grant writing / editing.
  • Record keeping of the experiments.
  • Presenting the results at scientific meetings.
  • Participate in weekly lab meetings, Journal Clubs and common seminars within the Department.
  • Perform other related duties and participate in special projects as assigned.
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