What are the responsibilities and job description for the Principal Scientist - Thousand Oaks, CA position at VetJobs?
Job Description
ATTENTION MILITARY AFFILIATED JOB SEEKERS - Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On-Site" at the location detailed in the job post.
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Principal Scientist
What you will do
Let's do this. Let's change the world. We are seeking a highly motivated Principal Scientist to join the Structural Biology group at our site in Thousand Oaks, CA. The Structural Biology group provides comprehensive molecular insights and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various therapeutic areas. The Principal Scientist will be responsible for structure determination of target molecules using X-ray crystallography and cryo-electron microscopy (cryo-EM). In this vital role you will be responsible for structure determination of target molecules using X-ray crystallography and cryo-electron microscopy (cryo-EM).
Interact directly with small molecule scientists including computational scientists, medicinal chemists, and protein engineers.
Apply knowledge to new areas of study, with strong interpersonal and communication skills to thrive in a highly collaborative environment.
Additional Qualifications / Responsibilities
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.
Basic Qualifications :
Ph.D. with a deep understanding of structural biology and general biochemistry and biophysics
Significant postdoctoral AND industrial (pharma / biotech) research experience, in large macromolecular complex structure determination. Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, structure determination and analysis
Proven expertise on protein crystallography AND cryo-EM single particle analysis, to determine atomic resolution structures
Experience with ubiquitin-proteasome system for protein degradation is a plus
Excellent presentation skills (written and oral) for effective team-based communication of results.
Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment
Willingness to take on new / unfamiliar responsibilities to help the team
Skills in managing multiple projects and capability to prioritize.
Preferred Qualifications :
Experience with other protein biochemical and / or biophysical characterization of protein complexes
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work / life balance, and career development opportunities that may include :
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Salary Range
134,813.00 USD - 161,617.00 USD
Salary : $134,813 - $161,617
