Director, Antibody Drug Discovery

The Company

SciNeuro Pharmaceuticals is a clinical-stage biotechnology company focused on developing disease-modifying

therapies for neurodegenerative diseases. Since its founding in 2020, SciNeuro has built a portfolio of pipeline

programs staged from discovery to early clinical development by addressing three key disease-driving

mechanisms of neurodegeneration neurovascular inflammation, proteinopathy, and immune response. These

interactive mechanisms allow for multiple and exciting treatment options for the various indications the company

is developing therapies for including Alzheimers disease, Parkinsons disease, and other devastating CNS diseases.

Since its founding in 2020, SciNeuro has already established itself as a recognized player in neurodegeneration.

SciNeuro has formed collaborations with GSK, Eli Lilly, and numerous other innovative partners who provide the

company with access to unique and differentiated technologies. With its $100M Series A financing round,

SciNeuro is backed by blue-chip investors led by ARCH Venture Partners and Lilly Asia Ventures.

For more information on SciNeuro, please click here.

The Position

We are seeking a VP, Antibody Drug Discovery who will lead the companys discovery & preclinical Biologics

research effort. The role encompasses scientific and drug discovery strategy, as well as people management and

leadership. The ability to work effectively within a multidisciplinary matrix environment, and an entrepreneurial

mindset, will be critical to success. The role will interface directly with SciNeuros executive management team

and will require effective teamwork and communication at all levels within the company, as well as representing a

key interface with SciNeuros external discovery collaborators.

What you will love about this Opportunity

A fast-growing company with great career advancement potential.

Great team and great science. You will be working with world-renowned neuroscientists and senior leaders from large

pharma/top CRO/CDMO and top academic medical centers with solid scientific, industrial, and managerial experience.

A company operating mainly in the US with a global footprint which could be a great learning experience to develop

skills in a multi-national environment.

A collaborative organization with cross-team communications internally covering different business units, and locations

and externally with vendors, partners, etc.

Title: VP, Antibody Drug Discovery

Location: Rockville, Maryland, USA

Key Responsibilities

Provide strategic input to executive management; lead SciNeuros large molecule research program/project(s), and

support overall R&D strategy by advancing projects in the current pipeline, as well as building the companys future

portfolio for CNS diseases.

Lead large molecule drug discovery programs from hit identification through Development Candidate selection and

validation, encompassing preclinical and clinical stage programs, including support for IND/BLA/NDA submissions.

Build R&D capabilities and bring in cutting-edge technologies to deliver first-in-class or best-in-class large molecule

assets.

Recruit, retain, and develop scientists and build teams to advance biological therapeutics research and development

programs.

Provide scientific leadership to the SciNeuro Biologics team, as well as external collaborators and research partners, for

example relating to experimental design; the implementation and execution of in vitro biological assays (biophysical,

biochemical, and cell-based); and in vivo testing in support of SciNeuros drug discovery programs.

Responsible for data review, analysis, and interpretation of in vitro and in vivo results, and troubleshooting issues

related to drug discovery projects.

Develop and manage project plans, timelines, and costs, and provide reports to executive management.

Core Qualifications and Experience

Ph.D. in biochemistry, cell biology, pharmacology, or a related field

8 years of relevant pharma/biotech experience (including postdoctoral, and fellowship training experience)

A broad and in-depth understanding of drug discovery and early-stage development is required

Experience in leading large molecule e.g. antibody drug discovery programs

Experience in identifying high-value therapeutic targets in multiple disease areas, based on the evaluation of biological

rationale, tractability, and the competitive landscape

Strong expertise in establishing in vitro biochemical/biophysical and cell-based assays and identifying translational

disease models

Ability to recruit, lead, manage, and motivate scientists (associate and PhD level) as a high performing team with deep

biologics expertise, as well as to work effectively across SciNeuros cross-functional R&D matrix.

Strong leadership and excellent management skills to oversee multiple projects for rapid progress, and timely

communication with upper management and relevant parties

A self-starter and team player who has resilience, and comfort with complexity and ambiguity

Excellent influencing and communication skills (oral and written)

Desired Additional Experience

CNS-related training or research experience

Extensive experience in a biotech start-up environment, including working with external partners.

Proven record for delivery of antibody programs from discovery to IND.

Experience/authorship of regulatory documentation & submissions

Total Compensation Package, including but not limited to:

Base Salary

Target Bonus

Long-term incentives including Employee Stock Ownership Plan (ESOP)

Benefits, including but not limited to:

A 401(k) retirement plan with company match.

Health insurance with Dependent Care

Life insurance

Dental & Vision insurance

Generous PTO accrual

Company Holidays

Parental leave

If you are interested, kindly send us your application to hr@scineuro.com