Demo

Staff Machine Learning Bioinformatics Scientist

X4 Life Sciences
Carlsbad, CA Full Time
POSTED ON 3/24/2025
AVAILABLE BEFORE 4/20/2025

About the Company :

Currently seeking a highly motivated and experienced computational scientist to join a dynamic biotech start up in San Diego. The successful candidate will lead innovative projects at the intersection of bioinformatics, machine learning, protein design , and experimental data analysis, contributing to groundbreaking advancements in biotechnology. This role requires a unique combination of technical expertise, strategic thinking, and collaboration with multidisciplinary teams.

About the Role :

Key Responsibilities :

  • Develop and deploy scalable bioinformatics solutions to address complex biological questions.
  • Design and train large language models (LLMs) for protein design and optimization, leveraging our unique capabilities to generate quantitative protein-protein interaction measurements at unprecedented scale.
  • Implement and drive iterative learning cycles between computational bioinformatics and experimental workflows, such as active learning or reinforcement learning approaches.
  • Analyze sequencing data from a variety of platforms, including Illumina, Oxford Nanopore, and PacBio, to extract meaningful insights.
  • Collaborate closely with experimental scientists to refine models and validate predictions through laboratory experiments.
  • Champion a high-quality, scalable code base by adhering to best practices in software development, including unit testing and continuous integration / continuous deployment (CI / CD).
  • Mentor junior scientists and contribute to fostering a culture of innovation and excellence within the team.

Qualifications :

Required Skills and Qualifications :

  • PhD in Computational Biology, Bioinformatics, Biophysics, Computer Science, or a related field with at least 5 years of relevant industry or postdoctoral experience.
  • Proven expertise in Python programming, with a strong track record of developing scalable and efficient bioinformatics pipelines.
  • Demonstrated experience in designing, training, and applying large language models to solve biological challenges, particularly in protein design.
  • Familiarity with active learning, reinforcement learning, or other iterative learning paradigms in scientific contexts.
  • Deep knowledge of sequencing technologies (Illumina, Oxford Nanopore, PacBio) and analysis methodologies.
  • Exceptional problem-solving skills and the ability to translate complex biological problems into computational solutions.
  • Excellent communication and collaboration skills, with a proven ability to work effectively within interdisciplinary teams.
  • Preferred Skills :

  • Experience with cloud computing platforms (AWS, GCP, or Azure) and containerization technologies (Docker, Apptainer).
  • Proficiency in machine learning frameworks such as TensorFlow or PyTorch.
  • Knowledge of structural bioinformatics and protein modeling tools.
  • Familiarity with laboratory techniques and experimental validation processes.
  • Pay range and compensation package :

  • 170,000 - $200,000
  • Bonus
  • Equity
  • Healthcare
  • Equal Opportunity Statement :

    Include a statement on commitment to diversity and inclusivity.

    Salary : $170,000 - $200,000

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