33 Senior Research Associate I- Proteomics Jobs in Cambridge, MA
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Senior Research Associate I- Proteomics
$128k-159k (estimate)
Full Time | Scientific Services
2 Weeks Ago
Broad Institute of MIT and Harvard is Hiring a Senior Research Associate I- Proteomics Near Cambridge, MA
General information
Location
Cambridge, MA
Ref #
40158
Job Family
Research
Workplace
On-Site
Date published
13-Jun-2024
Time Type
Full time
Description & RequirementsAre you interested in joining a dynamic team and contributing your talents to exciting new opportunities?
By submitting your resume, you'll be considered for our growing talent community within our Proteomics Platform at The Broad Institute of MIT & Harvard! This is a chance to connect with us and showcase your skills for current or upcoming positions in our Research Associate community. If your background aligns with a current or future need, a recruiter will reach out directly to discuss potential opportunities.
The Broad Institute Proteomics Group is looking for highly motivated research associates to develop and apply state-of-the-art proteomics technology to address compelling questions in biology, chemistry, and clinical medicine.
The specific research areas of immediate interest that this scientist could drive include:
The Broad Institute, and the embedded Proteomics Group, have an outstanding track record in training the next generation of research scientists and in developing and applying proteomic technologies critical to address important questions in biology and medicine. We collaborate with top-level researchers throughout the world, and results of these studies and our technology developments are published in top-tier journals.
Characteristic Duties
Location
Cambridge, MA
Ref #
40158
Job Family
Research
Workplace
On-Site
Date published
13-Jun-2024
Time Type
Full time
Description & RequirementsAre you interested in joining a dynamic team and contributing your talents to exciting new opportunities?
By submitting your resume, you'll be considered for our growing talent community within our Proteomics Platform at The Broad Institute of MIT & Harvard! This is a chance to connect with us and showcase your skills for current or upcoming positions in our Research Associate community. If your background aligns with a current or future need, a recruiter will reach out directly to discuss potential opportunities.
The Broad Institute Proteomics Group is looking for highly motivated research associates to develop and apply state-of-the-art proteomics technology to address compelling questions in biology, chemistry, and clinical medicine.
The specific research areas of immediate interest that this scientist could drive include:
- Detailed studies of cellular signaling networks related to protein phosphorylation, ubiquitylation, or acetylation
- Unveiling the targets of drugs or identifying protein interactors through chemical proteomics technologies and affinity purification MS
- Developing biological understanding of response and resistance to therapy
- Proteogenomic studies of a wide range of cancers
- Developing and optimizing new, broadly enabling proteomic technologies including targeted, quantitative MS assay development for proteins and modifications of high biological or clinical interest.
- Successful candidates will work in many of these areas together with an interdisciplinary team of clinicians, biologists, computational and proteomics scientists to deeply characterize and understand the proteomes of tumor-derived material, cells and biofluids.
- Bachelor’s degree in Chemistry or Biochemistry and 4 years of experience in a research laboratory, or a Master’s degree in analytical chemistry or biochemistry and 2 years of experience.
- 3 years of experience in MS-based proteomics; significant experience with MS, HPLC, peptide, and protein separation.
- High productivity, evidenced by high-quality collaborative science and research publications in peer-reviewed journals on which they are named co-authors.
- Able to work in a team.
- Excellent verbal and written communication skills.
- Knowledge of various scientific databases and experience with publishing and presenting experimental results are highly desirable.
- Experience in statistical and/or computational analysis of proteomics data.
- Post-translational modification analysis such as phosphorylation, ubiquitylation, etc.
- Cell biology/ biochemical methods to understand protein function.
The Broad Institute, and the embedded Proteomics Group, have an outstanding track record in training the next generation of research scientists and in developing and applying proteomic technologies critical to address important questions in biology and medicine. We collaborate with top-level researchers throughout the world, and results of these studies and our technology developments are published in top-tier journals.
Characteristic Duties
- Works with senior staff to set experimental strategy, project goals, and timelines and works directly with collaborator teams to drive projects toward successful completion.
- Helps define experimental design.
- Carries out detailed LC- and nanoLC-MS/MS analyses of complex, biologically derived protein, peptide and small molecule mixtures, including PTMs. Consults scientific literature and collaborates with other researchers from the scientific community as needed.
- Tracks and compiles results.
- Helps develop and optimize new technologies and protocols; assists with the training of lab personnel on new methodologies.
- Utilizes laboratory automation instrumentation to execute established proteomic workflows.
- Helps to produce and isolates samples for proteomics studies using cell culture techniques, immunoprecipitation, subcellular fractionation methods and protein sample preparation from tissues and/or biofluids.
- Utilizes other protein biochemistry and proteomic techniques such as western blotting, multidimensional chromatography and in-gel digestion to meet project and research goals.
- Operates and maintains one or more LC-mass spectrometers (Thermo QExactive/Exploris-series, Thermo Lumos-series, Bruker timsTOF) and HPLC systems for peptide separation and analysis.
- Helps ensure that project support, such as software, instrument spares, lab reagents, etc. are in place in accordance with project requirements.
- Prepares detailed technical documents describing procedures and results.
- Independently prepares posters and assists in preparation of reports and manuscripts for meetings and peer-reviewed literature.
- Will assist supervisory scientists and collaborators with writing and editing as needed.
- Orders supplies, helps to maintain stock of common expendables and reagents for Proteomics lab.
Job Summary
JOB TYPE
Full Time
INDUSTRY
Scientific Services
SALARY
$128k-159k (estimate)
POST DATE
08/29/2024
EXPIRATION DATE
09/26/2024
WEBSITE
broadinstitute.org
HEADQUARTERS
CAMBRIDGE, MA
SIZE
500 - 1,000
FOUNDED
1990
TYPE
NGO/NPO/NFP/Organization/Association
CEO
ERIC LANDER
REVENUE
$500M - $1B
INDUSTRY
Scientific Services
Related Companies
About Broad Institute of MIT and Harvard
Broad Institute is a biomedical research center that develops a genomics-based treatment for cancer, cardiovascular and infectious diseases.
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