Title: Research Associate-Bioprocess

Location: Bothell, WA

Duration: 3 years

Job Description:

• This role will be primarily responsible for supporting the Upstream cell culture operations in our pilot-scale lab (up to 250L) to generate protein materials needed for cross-functional developments as well as GLP toxicology studies.
• This role will be expected to independently execute cell culture process from harvest to final fill and to be cross trained in Downstream purification processes.
• This role will also partially support activities in the Purification Process Development lab (15-20%).
• Support protein material generation activities, including both mammalian cell culture and purification operations, from cell thaw to final formulated mAb.
• Escalate equipment or process issues as necessary. Help in troubleshooting and derivation of appropriate corrective action and resolution.
• Prepare buffer and media solutions to support material generation and process development runs.
• Perform equipment (e.g., bioreactor, purification skid, pH meters, and chromatography column, etc.) maintenance.
• Maintain accurate and detailed records of all lab activities and work routinely with electronic data records and applications.
• Generate technical reports and present them in internal meetings.
• Purchase raw materials and consumables.
• Hands-on cell culture experience includes operating both bench-top glass vessel, large-scale single-use bioreactor systems, and associated activities.
• Familiarity with lab software and/or electronic lab notebooks (ELN).
• Able to lift and move 50 lbs. Repeatedly.
• Weekend and holiday work is required when needed.
• Familiar with purification process and operations.
• Proficient in lab automation.
• Proficiency with ELN and data management (Benchling).
• Biomanufacturing experience.
• Mammalian cell culture (Pilot)
• Buffer and Media Prep
• Lab Eq Maintenance

What is the minimum education experience required? Prefer BS.

Associate degree with 2 years exp.